CAS 160369-84-6

N-Acetyl-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-L-valinamide

Description:

N-Acetyl-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-L-valinamide, with the CAS number 160369-84-6, is a synthetic compound that belongs to the class of peptides and peptide derivatives. This substance features a complex structure characterized by the presence of an N-acetyl group, which enhances its solubility and stability. The compound contains two amino acid residues, L-leucine and L-valine, contributing to its biological activity and potential interactions with biological systems. The presence of a formyl group attached to a phenylethyl moiety suggests potential reactivity and specificity in biochemical applications. This compound may exhibit properties such as antimicrobial or antitumor activity, making it of interest in pharmaceutical research. Its stereochemistry, indicated by the (1S) configuration, is crucial for its biological function, as the spatial arrangement of atoms can significantly influence the compound's interactions with biological targets. Overall, N-Acetyl-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-L-valinamide represents a noteworthy example of modified peptides with potential therapeutic applications.

Formula: C₂₂H₃₃N₃O₄

InChI: InChI=1S/C22H33N3O4/c1-14(2)11-19(23-16(5)27)21(28)25-20(15(3)4)22(29)24-18(13-26)12-17-9-7-6-8-10-17/h6-10,13-15,18-20H,11-12H2,1-5H3,(H,23,27)(H,24,29)(H,25,28)/t18-,19-,20-/m0/s1

InChI key: InChIKey=AWIJCYLMKAQLHO-UFYCRDLUSA-N

SMILES: [C@@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C=O)=O)C(C)C)=O)(CC(C)C)NC(C)=O

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Valinamide, N-acetyl-<smallcap>L</span>-leucyl-N-(1-formyl-2-phenylethyl)-, (S)-
• <span class="text-smallcaps">L</smallcap>-Valinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-
• Ac-Leu-Val-L-Phenylalaninal
• Ac-Leu-Val-Phenylalaninal
• Hiv Protease Inhibitor
• N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-<smallcap>L</span>-valinamide
• N-Acetyl-Leu-Val-Phe-al
• N-Acetyl-Leu-Val-Phenylalaninal
• N-Acetyl-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-L-valinamide
• L-Valinamide, N-acetyl-L-leucyl-N-(1-formyl-2-phenylethyl)-, (S)-
• L-Valinamide, N-acetyl-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-

Ac-Leu-Val-Phe-aldehyde

CAS: 160369-84-6

Ac-Leu-Val-Phe-aldehyde is a synthetic compound that inhibits the catalytic activity of carboxyl enzymes. It binds to the catalytic site of the enzyme via a noncovalent interaction with residues on the polypeptide chain, thereby preventing the formation of an active complex with other cofactors such as metal ions, amino acids, and ATP. Ac-Leu-Val-Phe-aldehyde can be used in analytical chemistry for determination of carboxyl groups in organic compounds or for determining protein content in biological samples. Ac-Leu-Val-Phe-aldehyde has also been shown to bind to antibodies which are specific for carboxyl groups.

Formula: C₂₂H₃₃N₃O₄

Purity: Min. 95%

Molecular weight: 403.52 g/mol

Ref: 3D-FA111046