CAS 1603833-55-1

1H-Indole-2-carboxamide, 5-[(3R)-1-acetyl-3-piperidinyl]-N-(3,5-difluorophenyl)-

Formula: C₂₂H₂₁F₂N₃O₂

Synonyms:

• 1H-Indole-2-carboxamide, 5-[(3R)-1-acetyl-3-piperidinyl]-N-(3,5-difluorophenyl)-

Amyloid-β-IN-2

CAS: 1603833-55-1

Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.

Formula: C₂₂H₂₁F₂N₃O₂

Color and Shape: Solid

Molecular weight: 397.42

Ref: TM-T207418