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CAS 1603833-56-2

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  • Amyloid-β-IN-3
    Targetmol
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    Amyloid-β-IN-3

    CAS:
    <p>Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.</p>
    Formula:C22H21F2N3O2
    Color and Shape:Solid
    Molecular weight:397.42

    Ref: TM-T207233