Bacitracin B is a polypeptide antibiotic that is primarily derived from the bacterium Bacillus subtilis. It is known for its effectiveness against a variety of Gram-positive bacteria, making it valuable in both clinical and agricultural applications. Bacitracin B functions by inhibiting bacterial cell wall synthesis, which ultimately leads to cell lysis and death. The compound is typically used topically due to its potential toxicity when administered systemically. It is often found in ointments and creams for treating minor skin infections and is also used in veterinary medicine. Bacitracin B is characterized by its relatively low solubility in water, which can affect its formulation in pharmaceutical products. Additionally, it is important to note that while bacitracin is effective against certain bacteria, it is not effective against Gram-negative bacteria. Safety considerations include potential allergic reactions and the development of antibiotic resistance, which necessitates careful use and monitoring in both human and animal health contexts.

bacithrocin B

160433-51-2: Bacitracin B is a polypeptide antibiotic that is primarily derived from the bacterium Bacillus subtilis. It is known for its effectiveness against a variety of Gram-positive bacteria, making it valuable in both clinical and agricultural applications. Bacitracin B functions by inhibiting bacterial cell wall synthesis, which ultimately leads to cell lysis and death. The compound is typically used topically due to its potential toxicity when administered systemically. It is often found in ointments and creams for treating minor skin infections and is also used in veterinary medicine. Bacitracin B is characterized by its relatively low solubility in water, which can affect its formulation in pharmaceutical products. Additionally, it is important to note that while bacitracin is effective against certain bacteria, it is not effective against Gram-negative bacteria. Safety considerations include potential allergic reactions and the development of antibiotic resistance, which necessitates careful use and monitoring in both human and animal health contexts.

<p>Bacithrocin B is a thrombin inhibitor that suppresses the activity of thrombin, Factor Xa, trypsin, and papain, with IC50 values of 84 μM, 17 μM, 1.7 μM, and 0.02 μM, respectively.</p>

CAS 160433-51-2

bacithrocin B

Bacithrocin B

Ref: TM-TN10738