CAS 160488-53-9

(S)-Pantoprazole sodium

Description:

(S)-Pantoprazole sodium is a proton pump inhibitor primarily used to treat gastroesophageal reflux disease (GERD) and other conditions associated with excessive stomach acid production. It is a sodium salt of the (S)-enantiomer of pantoprazole, which is a substituted benzimidazole. This compound exhibits a chiral center, contributing to its specific pharmacological activity. In its solid form, (S)-Pantoprazole sodium is typically a white to off-white crystalline powder, soluble in water and slightly soluble in organic solvents. The substance works by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, leading to a decrease in gastric acid secretion. Its pharmacokinetics include rapid absorption and a relatively long half-life, allowing for once-daily dosing. The compound is generally well-tolerated, though potential side effects may include gastrointestinal disturbances and headache. As with all medications, it is essential to use (S)-Pantoprazole sodium under medical supervision to ensure safety and efficacy.

Formula: C₁₆H₁₅F₂N₃NaO₄S

Synonyms:

• 6-(Difluoromethoxy)-2-[(S)-[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
• (S)-(-)-Pantoprazole sodium

6-(Difluoromethoxy)-2-[(S)-[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt

CAS: 160488-53-9

Formula: C₁₆H₁₄F₂N₃NaO₄S

Purity: 99%

Color and Shape: Solid

Molecular weight: 405.3516

Ref: IN-DA00ADTA

(S)-(-)-Pantoprazole Sodium Salt

Controlled Product

CAS: 160488-53-9

Stability Hygroscopic
Applications The S-enantiomer of Pantoprazole (P183000).
References Simon, W.A., et al.: Biochem. Pharmacol., 39, 1799 (1990),

Formula: C₁₆H₁₄F₂N₃O₄S·Na

Color and Shape: Neat

Molecular weight: 405.35

Ref: TR-P182995

Sodium (S)-6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide

CAS: 160488-53-9

Purity: 97%

Molecular weight: 405.3500061035156

Ref: 10-F689506

(S)-(-)-Pantoprazole sodium

CAS: 160488-53-9

Pantoprazole sodium is a proton pump inhibitor that inhibits the production of gastric acid by blocking the H+/K+-ATPase enzyme. It has been shown to be effective in treating gastroesophageal reflux disease (GERD) and peptic ulcers. Pantoprazole sodium is available as a sodium salt, which is an ester of pantoprazole and sodium hydroxide. This product crystallizes from ethyl acetate or recrystallizes from acetonitrile. Pantoprazole sodium is chiral, meaning it has two forms that are non-superimposable mirror images of each other. The (S)-(-)-pantoprazole sodium form is the more potent form and is used in this product.

Formula: C₁₆H₁₄F₂N₃NaO₄S

Purity: Min. 95%

Molecular weight: 405.35 g/mol

Ref: 3D-FD26754

(S)-(-)-Pantoprazole-d7 Sodium Salt

Controlled Product

CAS: 160488-53-9

Formula: C₁₆H₇D₈F₂N₃NaO₄S

Color and Shape: Neat

Molecular weight: 412.39

Ref: TR-P182997