CAS 160552-54-5

2(1H)-Pyrimidinone,4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- (9CI)

Description:

2(1H)-Pyrimidinone, 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- (9CI), with CAS number 160552-54-5, is a chemical compound characterized by its pyrimidinone core structure, which features a pyrimidine ring with a carbonyl and amino group. This compound also contains a substituted oxathiolane ring, which contributes to its unique properties. The presence of the hydroxymethyl group and the oxido functionality indicates potential for hydrogen bonding and reactivity, making it of interest in medicinal chemistry. Its stereochemistry, denoted by the (2R,3R,5S) configuration, suggests specific spatial arrangements that can influence biological activity and interactions with enzymes or receptors. This compound may exhibit properties relevant to antiviral or antibacterial activities, as many pyrimidine derivatives are known for their pharmacological significance. Overall, the structural features of this compound suggest it could play a role in drug development, particularly in the context of nucleoside analogs or other therapeutic agents.

Formula: C₈H₁₁N₃O₄S

Synonyms:

• 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, S-oxide, [2R-(2a,3b,5a)]-
• 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
• 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-, [2R-(2a,3b,5a)]-
• Gi 138870X

Lamivudine R-sulfoxide ((4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one S-oxide)

CAS: 160552-54-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₈H₁₁N₃O₄S

Color and Shape: White Off-White Powder

Molecular weight: 245.04703

Ref: 45-1A05120

Lamivudine EP Impurity H

CAS: 160552-54-5

Formula: C₈H₁₁N₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 245.25

Ref: 4Z-L-2010

Lamivudine (R)-Sulfoxide

Controlled Product

CAS: 160552-54-5

Impurity Lamivudine EP Impurity H
Stability Hygroscopic
Applications Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977)

Formula: C₈H₁₁N₃O₄S

Color and Shape: Neat

Molecular weight: 245.26

Ref: TR-L172475

Lamivudine EP Impurity H

CAS: 160552-54-5

Formula: C₈H₁₁N₃O₄S

Molecular weight: 245.25

Ref: ST-EA-CP-L3008

Lamivudine sulfoxide, (R)-

CAS: 160552-54-5

(R)-Lamivudine sulfoxide is a metabolite of Lamivudine, an antiviral used to treat chronic hepatitis B.

Formula: C₈H₁₁N₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 245.26

Ref: TM-T20591

Lamivudine (R)-Sulfoxide

CAS: 160552-54-5

Please enquire for more information about Lamivudine (R)-Sulfoxide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₈H₁₁N₃O₄S

Purity: Min. 95%

Molecular weight: 245.26 g/mol

Ref: 3D-KGA55254