CAS 16064-08-7

6-Iodo-4(3H)-quinazolinone

Description:

6-Iodo-4(3H)-quinazolinone is a heterocyclic organic compound characterized by its quinazolinone structure, which features a fused benzene and pyrimidine ring system. The presence of an iodine atom at the 6-position of the quinazolinone ring significantly influences its chemical reactivity and biological activity. This compound typically exhibits properties such as being a solid at room temperature, with moderate solubility in organic solvents. It is often utilized in medicinal chemistry due to its potential pharmacological properties, including antimicrobial and anticancer activities. The compound's structure allows for various functional group modifications, making it a versatile building block in drug development. Additionally, its synthesis often involves methods such as cyclization reactions, and it can be analyzed using techniques like NMR spectroscopy and mass spectrometry to confirm its identity and purity. Overall, 6-Iodo-4(3H)-quinazolinone represents an important compound in the field of organic and medicinal chemistry, with ongoing research into its applications and mechanisms of action.

Formula: C₈H₅IN₂O

InChI: InChI=1S/C8H5IN2O/c9-5-1-2-7-6(3-5)8(12)11-4-10-7/h1-4H,(H,10,11,12)

InChI key: InChIKey=PUGXMZKDRVGIHC-UHFFFAOYSA-N

SMILES: O=C1C=2C(=CC=C(I)C2)NC=N1

Synonyms:

• 4(1H)-Quinazolinone, 6-iodo-
• 4(3H)-Quinazolinone, 6-iodo-
• 4-Quinazolinol, 6-iodo-
• 6-Iodo-1H-Quinazolin-4-One
• 6-Iodo-3,4-dihydroquinazolin-4-one
• 6-Iodo-3H-Quinazolin-4-One
• 6-Iodo-4(3H)-quinazolinone
• 6-Iodo-4-Quinazolone
• 6-Iodoquinazolin-4(1H)-One
• 6-Iodoquinazolin-4-One
• 6-Iodoquinazolinone

6-Iodo-4-hydroxyquinazoline

CAS: 16064-08-7

Formula: C₈H₅IN₂O

Purity: >97.0%(GC)(T)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 272.05

Ref: 3B-I0832

6-Iodoquinazolin-4-one

CAS: 16064-08-7

Formula: C₈H₅IN₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 272.0426

Ref: IN-DA003N8Y

6-Iodoquinazolin-4-one

CAS: 16064-08-7

6-Iodoquinazolin-4-one

Purity: 97%

Molecular weight: 272.04g/mol

Ref: 54-OR350208

6-Iodoquinazolin-4-one

Controlled Product

CAS: 16064-08-7

Applications 6-Iodoquinazolin-4-one is an intermediate in the synthesis of Lapatinib (L175800).
References Petrov, K., et al.: Bioorg. Med. Chem. Lett., 16, 4686 (2006),

Formula: C₈H₅IN₂O

Color and Shape: Neat

Molecular weight: 272.05

Ref: TR-I719580

6-IODOQUINAZOLIN-4-OL

CAS: 16064-08-7

Formula: C₈H₅IN₂O

Purity: 95%

Color and Shape: Slightly pale purple to pale purple powder

Molecular weight: 272.045

Ref: 10-F333500