CAS 16066-84-5

tert-butyl methylcarbamate

Description:

Tert-butyl methylcarbamate, with the CAS number 16066-84-5, is an organic compound that belongs to the class of carbamates. It is characterized by its structure, which includes a tert-butyl group and a methyl carbamate moiety. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and specific conditions. Tert-butyl methylcarbamate is known for its use as a reagent in organic synthesis, particularly in the protection of amines during chemical reactions. It exhibits moderate solubility in organic solvents and is relatively stable under standard conditions. However, like many carbamates, it may undergo hydrolysis in the presence of water, leading to the formation of the corresponding amine and carbon dioxide. Safety considerations include potential toxicity and the need for proper handling to avoid inhalation or skin contact. Overall, tert-butyl methylcarbamate is a valuable compound in synthetic organic chemistry, particularly in the context of protecting functional groups.

Formula: C₆H₁₃NO₂

InChI: InChI=1/C6H13NO2/c1-6(2,3)9-5(8)7-4/h1-4H3,(H,7,8)

SMILES: CC(C)(C)OC(=NC)O

Synonyms:

• Carbamic acid, N-methyl-, 1,1-dimethylethyl ester
• Methyl-carbamic acid tert-butyl ester
• tert-Butyl methylcarbamate

Carbamic acid, N-methyl-, 1,1-dimethylethyl ester

CAS: 16066-84-5

Formula: C₆H₁₃NO₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 131.1729

Ref: IN-DA001S3M

tert-Butyl methylcarbamate

CAS: 16066-84-5

tert-Butyl methylcarbamate

Formula: C₆H₁₃NO₂

Purity: 95%

Color and Shape: clear. colourless liquid

Molecular weight: 131.17g/mol

Ref: 54-OR61100

tert-Butyl N-methylcarbamate

CAS: 16066-84-5

Formula: C₆H₁₃NO₂

Purity: 96%

Color and Shape: Liquid, Oil

Molecular weight: 131.175

Ref: 10-F044201

tert-Butyl Methylcarbamate

Controlled Product

CAS: 16066-84-5

Applications tert-Butyl Methylcarbamate is an substituent in the synthetic preparation of PF-06463922, a macrocyclic inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1).
References Johnson, T. W., et al.: J. Med. Chem., 57, 4720 (2014);

Formula: C₆H₁₃NO₂

Color and Shape: Neat

Molecular weight: 131.17

Ref: TR-B694020

tert-Butyl-N-methylcarbamate

CAS: 16066-84-5

tert-Butyl-N-methylcarbamate is an amine that is used in the preparation of styrene. It is a ligand and can be used as a sodium hydrogen amide in an amination reaction. The tert-butyl group can be replaced with other substituents, such as carboxylic acid, ester, or nitrile to produce different functionalities. Tert-butyl-N-methylcarbamate is also used to prepare nicotine from hydrogen sulfate.

Formula: C₆H₁₃NO₂

Purity: Min. 95%

Molecular weight: 131.17 g/mol

Ref: 3D-RAA06684