Description:5-Iodo-1H-indole is a chemical compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of an iodine atom at the 5-position of the indole ring significantly influences its chemical properties and reactivity. This compound is typically a solid at room temperature and is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its biological activity. It may exhibit properties such as fluorescence and can participate in various chemical reactions, including electrophilic substitutions and coupling reactions. The iodine substituent can enhance the compound's lipophilicity, potentially affecting its bioavailability and interaction with biological targets. Additionally, 5-iodo-1H-indole can serve as a useful intermediate in organic synthesis, allowing for the introduction of other functional groups. As with many halogenated compounds, it is important to handle it with care, considering its potential toxicity and environmental impact.
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