CAS 1607007-18-0

Tenofovir Dimer Triethylammonium Salt

Description:

Tenofovir Dimer Triethylammonium Salt is a chemical compound primarily known for its role as an antiviral agent, particularly in the treatment of HIV and hepatitis B infections. It is a prodrug of tenofovir, which means it is converted into the active form within the body. The compound features a dimeric structure, enhancing its pharmacological properties. As a triethylammonium salt, it possesses a quaternary ammonium group, which contributes to its solubility and stability in aqueous solutions. This characteristic is crucial for its bioavailability and effectiveness in therapeutic applications. The compound is typically administered orally and is known for its favorable pharmacokinetic profile, including a long half-life, which allows for once-daily dosing. Additionally, it exhibits a high barrier to resistance, making it a valuable option in antiretroviral therapy. Safety profiles indicate that it is generally well-tolerated, although, like all medications, it may have potential side effects that require monitoring. Overall, Tenofovir Dimer Triethylammonium Salt represents a significant advancement in antiviral treatment strategies.

Formula: C₁₈H₂₆N₁₀O₇P₂

Synonyms:

• 9-[(R) -2-methoxypropyl phosphate]-adenine dianhydride
• TAF Impurity D
• Tenofovir alafenamide-18
• Tenofovir impurity P0Z19 (PMPA anhydride)
• Diphosphonic acid, P,P'-bis[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-
• bis((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)diphosphonic acid, diammonia salt
• Tenofovir related Impurity 3
• Tenofovir Alafenamide PMPA Impurity
• Tenofovir related Impurity 3（Tenofovir Alafenamide Impurity 8）
• Tenofovir Alafenamide Impurity 12
• bis((((S)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)diphosphonic acid

Tenofovir Dimer Disodium Salt

CAS: 1607007-18-0

Formula: C₁₈H₂₄N₁₀O₇P₂·2Na

Color and Shape: White To Off-White Solid

Molecular weight: 554.40 2*22.99

Ref: 4Z-T-0252

Tenofovir Impurity 68

CAS: 1607007-18-0

Formula: C₁₈H₂₆N₁₀O₇P₂

Color and Shape: White To Off-White Solid

Molecular weight: 556.42

Ref: 4Z-T-02113

Tenofovir Dimer

CAS: 1607007-18-0

Formula: C₁₈H₂₆N₁₀O₇P₂

Molecular weight: 556.41

Ref: ST-EA-CP-T5009

Tenofovir Dimer Triethylammonium Salt

Controlled Product

CAS: 1607007-18-0

Stability Very Hygroscopic
Applications Tenofovir Dimer is a dimer of Tenofovir (T018500). Tenofovir is a reverse transcriptase inhibitor. Used as an anti-HIV agent.
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),

Formula: C₃₀H₅₆N₁₂O₇P₂

Color and Shape: Neat

Molecular weight: 758.79

Ref: TR-T018485

Tenofovir dimer triethylammonium salt

CAS: 1607007-18-0

Tenofovir dimer triethylammonium salt is a potent inhibitor of protein kinase that has been shown to induce apoptosis in cancer cells. This Chinese medicinal analog has been found to be effective against various types of cancer, including bladder, prostate, and breast cancer. Tenofovir dimer triethylammonium salt works by inhibiting the activity of enzymes involved in cell cycle regulation and inducing cell death through apoptotic pathways. This drug is also an effective inhibitor of HIV-1 replication and is used as an antiviral agent. In addition to being an anticancer and antiviral drug, Tenofovir dimer triethylammonium salt has also been reported to have potential therapeutic applications for other diseases such as hepatitis B virus infection and osteoporosis.

Formula: C₁₈H₂₆N₁₀O₇P₂

Purity: Min. 95%

Molecular weight: 556.4 g/mol

Ref: 3D-HPC00718