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CAS 160751-44-0

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N-ALFA-FMOC-4-(PHOSPHONODIFLUOROMETHYL)-L-PHENYLALANINE

Description:
N-ALFA-FMOC-4-(PHOSPHONODIFLUOROMETHYL)-L-PHENYLALANINE, with CAS number 160751-44-0, is a synthetic amino acid derivative that features a phenylalanine backbone modified with a phosphonodifluoromethyl group and a fluorenylmethyloxycarbonyl (FMOC) protective group. The FMOC group is commonly used in peptide synthesis to protect the amino group, allowing for selective reactions at the carboxyl end. The presence of the phosphonodifluoromethyl moiety introduces unique properties, potentially enhancing biological activity or specificity in biochemical applications. This compound is typically utilized in research settings, particularly in the development of peptide-based therapeutics or as a building block in the synthesis of more complex molecules. Its characteristics include stability under standard laboratory conditions, solubility in organic solvents, and reactivity that can be tailored through the manipulation of its functional groups. As with many synthetic compounds, safety data should be consulted to ensure proper handling and usage in laboratory environments.
Formula:C29H30F2NO7P
InChI:InChI=1/C29H30F2NO7P/c1-3-38-40(36,39-4-2)29(30,31)20-15-13-19(14-16-20)17-26(27(33)34)32-28(35)37-18-25-23-11-7-5-9-21(23)22-10-6-8-12-24(22)25/h5-16,25-26H,3-4,17-18H2,1-2H3,(H,32,35)(H,33,34)/t26-/m0/s1
SMILES:CCOP(=O)(C(c1ccc(cc1)C[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)(F)F)OCC
Synonyms:
  • 4-(Difluorophosphonomethyl)-N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Phenylalanine
  • (4-(Diethylphosphono)Difluoromethyl)-N-(Fluoren-9-Yl-Methoxycarbonyl)-L-Phenylalanine
  • 4-[(Dithylphosphono)Difluoromethyl]-N-(Fluoren-9-Ylmethoxycarbonyl)-L-Phenylalamine
  • N-Alpha-9-Fluorenylcarbonyl-4-(Diethylphosphonodifluoromethyl)-L-Phenylalanine
  • N-Alpha-Fmoc-4-(Phosphonodifluoromethyl)-L-Phenylalanine
  • 4-(Diethylphosphono)Difluoromethyl)-N-(Fluoren-9-Yl-Methoxycarbony)-L-Phenylalanine
  • N-Alfa-Fluorenylcarbonyl-4-(Diethylphosphonodifluoromethyl)-L-Phenylalanine
  • 4-[(diethoxyphosphoryl)(difluoro)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
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