CAS 16082-59-0

N-(Quinolin-8-yl)benzenesulfonamide

Description:

N-(Quinolin-8-yl)benzenesulfonamide, with the CAS number 16082-59-0, is a chemical compound characterized by its sulfonamide functional group attached to a quinoline moiety. This compound typically exhibits a solid state at room temperature and is known for its potential biological activity, particularly in medicinal chemistry. The presence of the quinoline ring contributes to its aromatic properties, while the sulfonamide group can enhance solubility and reactivity. It may exhibit various pharmacological effects, making it of interest in drug development, particularly in the fields of antimicrobial and anti-inflammatory research. The compound's structure allows for interactions with biological targets, which can be explored through various assays. Additionally, its stability and solubility in different solvents can vary, influencing its application in laboratory settings. As with many sulfonamides, it may also be subject to specific regulatory considerations due to its potential biological effects. Overall, N-(Quinolin-8-yl)benzenesulfonamide represents a valuable compound in the study of chemical and biological interactions.

Formula: C₁₅H₁₂N₂O₂S

InChI: InChI=1S/C15H12N2O2S/c18-20(19,13-8-2-1-3-9-13)17-14-10-4-6-12-7-5-11-16-15(12)14/h1-11,17H

InChI key: InChIKey=FEBBZFJWAMUFPI-UHFFFAOYSA-N

SMILES: N(S(=O)(=O)C1=CC=CC=C1)C=2C3=C(C=CC2)C=CC=N3

Synonyms:

• 8-(Phenylsulfonylamino)quinoline
• 8-(p-Benzenesulfonylamino)quinoline
• 8-Benzenesulfonamidoquinoline
• Benzenesulfonamide, N-8-quinolinyl-
• Benzenesulfonamide, N-8-quinolyl-
• N-(quinolin-8-yl)benzenesulfonamide
• N-8-Quinolinylbenzenesulfonamide
• 8-(4-Benzenesulfonylamino)quinoline

8-(4-Benzenesulfonylamino)quinoline

CAS: 16082-59-0

8-(4-Benzenesulfonylamino)quinoline is an anti-diabetic agent that inhibits the release of glucose from liver cells. It has been shown to be effective in hamsters with alloxan-induced diabetes. 8-(4-Benzenesulfonylamino)quinoline blocks the production of glucose by inhibiting the activity of pancreatic beta cells, which produce insulin and secrete it into the bloodstream. The drug binds specifically to these cells and prevents insulin secretion, thereby decreasing blood glucose levels. This agent can also interact with ascorbate (vitamin C), an extractant used to purify 8-(4-benzenesulfonylamino)quinoline, forming hydrogen peroxide (H2O2). The H2O2 formed may cause some damage to animal tissues when used for extraction purposes.

Formula: C₁₅H₁₂N₂O₂S

Purity: Min. 95%

Molecular weight: 284.3 g/mol

Ref: 3D-RAA08259