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CAS 1609356-99-1

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  • Lentztrehalose A
    Targetmol
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    Lentztrehalose A

    CAS:
    <p>Lentztrehalose A, a disaccharide microbial metabolite identified in Lentzea, exhibits a range of biological activities. This compound specifically inhibits M. smegmatis trehalase—an enzyme involved in trehalose metabolism—more effectively than trehalase from porcine kidney, with IC50 values of 0.67 mM and &gt;20 mM, respectively. Additionally, Lentztrehalose A at a concentration of 100 mM promotes autophagy in MeWo melanoma and OVK18 ovarian cancer cells. When administered at 50 mg/kg daily, it enhances survival rates and impedes tumor growth in a Sarcoma 180 murine sarcoma model.</p>
    Formula:C17H32O13
    Color and Shape:Solid
    Molecular weight:444.43

    Ref: TM-TN7283