CAS 1609452-30-3

7,8-Dibromo-5,6-dihydro-9-methyl-2-(1-piperazinyl)-4H-imidazo[4,5,1-ij]quinoline hydrochloride

CAS: 1609452-30-3

Formula: C₁₅H₁₉Br₂ClN₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 450.5992

Ref: IN-DA01EOQ6

SEL120-34A HCl

CAS: 1609452-30-3

SEL120-34A HCl

Purity: ≥98%

Molecular weight: 450.6g/mol

Ref: 54-BUP02496

SEL120-34A HCl

CAS: 1609452-30-3

SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectively

Formula: C₁₅H₁₉Br₂ClN₄

Purity: 98.13% - 98.47%

Color and Shape: Solid

Molecular weight: 450.6

Ref: TM-T10744L

SEL120-34A hydrochloride

CAS: 1609452-30-3

Sel120-34A hydrochloride is an orally active anticancer agent that inhibits the proliferation of cancer cells and induces apoptosis. Sel120-34A hydrochloride has been shown to synergistically interact with venetoclax, a Bcl-2 inhibitor, in vitro and in vivo, resulting in potent inhibition of cancer cell growth. Sel120-34A hydrochloride also shows cytostatic effects on cancer cells. Sel120-34A hydrochloride inhibits histone H3 phosphorylation at serine 10 and serine 14, leading to transcriptional repression and subsequent cell death. Sel120-34A hydrochloride has been found to be effective in inhibiting the growth of colon cancer cells when applied as coatings or when exposed to light.

Formula: C₁₅H₁₉Br₂ClN₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 450.6 g/mol

Ref: 3D-JPC45230

SEL120-34A HCl

CAS: 1609452-30-3

SEL120-34A HCl

Purity: 99%

Molecular weight: 450.60g/mol

Ref: 54-BISN0066