CAS 161058-83-9

6-(Cyclohexylmethoxy)-9H-purin-2-ylamine

Description:

6-(Cyclohexylmethoxy)-9H-purin-2-ylamine, with the CAS number 161058-83-9, is a purine derivative characterized by its unique structural features that include a purine base and a cyclohexylmethoxy group. This compound typically exhibits properties associated with purines, such as potential biological activity, particularly in relation to nucleic acid metabolism and signaling pathways. The presence of the cyclohexylmethoxy substituent may influence its solubility, stability, and interaction with biological targets, potentially enhancing its pharmacological profile. In terms of physical properties, it may exhibit moderate to high lipophilicity due to the cyclohexyl group, which can affect its absorption and distribution in biological systems. Additionally, the compound may participate in hydrogen bonding due to the amine group, which could play a role in its binding affinity to specific receptors or enzymes. Overall, this compound's characteristics suggest potential utility in medicinal chemistry, particularly in the development of therapeutics targeting purine-related pathways.

Formula: C₁₂H₁₇N₅O

InChI: InChI=1/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17)

SMILES: C1CCC(CC1)COc1c2c([nH]cn2)[nH]c(=N)n1

Synonyms:

• Nu-2058
• 6-(Cyclohexylmethyl)guanine
• 6-(cyclohexylmethoxy)-7H-purin-2-amine
• Nu2058

NU 2058

CAS: 161058-83-9

Formula: C₁₂H₁₇N₅O

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 247.30

Ref: 3B-N0958

9H-Purin-2-amine, 6-(cyclohexylmethoxy)-

CAS: 161058-83-9

Formula: C₁₂H₁₇N₅O

Purity: 98%

Color and Shape: Solid

Molecular weight: 247.2963

Ref: IN-DA001VLL

NU2058

CAS: 161058-83-9

NU2058

Purity: ≥98%

Molecular weight: 247.3g/mol

Ref: 54-BUP13337

6-(Cyclohexylmethoxy)-9H-Purin-2-Amine

CAS: 161058-83-9

6-(Cyclohexylmethoxy)-9H-Purin-2-Amine

Purity: 98%

Molecular weight: 247.3g/mol

Ref: 54-OR1026466

NU2058

CAS: 161058-83-9

Formula: C₁₂H₁₇N₅O

Molecular weight: 247.30

Ref: 7W-GK6680

NU2058

CAS: 161058-83-9

NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.

Formula: C₁₂H₁₇N₅O

Purity: 99.34% - 99.92%

Color and Shape: Solid

Molecular weight: 247.3

Ref: TM-T3186

6-(Cyclohexylmethoxy)-9H-purin-2-amine

CAS: 161058-83-9

Formula: C₁₂H₁₇N₅O

Purity: 99%

Molecular weight: 247.302

Ref: 10-F436931

NU2058

CAS: 161058-83-9

NU2058 is a fatty acid that has been shown to inhibit the replication of various viruses. It also inhibits viral infection by binding to and inhibiting the activity of the viral protein NS3 helicase. NU2058 has been shown to have antiviral activity against HIV-1, and it also inhibits human papillomavirus (HPV) infections in vivo. NU2058 is active against some strains of influenza virus and herpes simplex virus type 1 (HSV-1). This compound also inhibits cell proliferation in vitro and restenosis in vivo. In addition, NU2058 has been shown to inhibit breast cancer cells resistant to taxanes or anthracyclines.

Formula: C₁₂H₁₇N₅O

Purity: Min. 95%

Molecular weight: 247.3 g/mol

Ref: 3D-LGA05883