Immunoglobulin G1 (IgG1) is a type of antibody that plays a crucial role in the immune response by recognizing and binding to specific antigens. The substance in question is a monoclonal antibody targeting the human CC chemokine receptor CCR2, which is involved in immune cell signaling and inflammation. This particular antibody is a dimer, meaning it consists of two identical units linked by disulfide bonds, enhancing its stability and functionality. The heavy chain is derived from a mouse (Mus musculus) source, while the kappa chain is also of murine origin, indicating its hybridoma technology-based production. The specificity for CCR2 suggests potential applications in therapeutic interventions for conditions involving this receptor, such as certain inflammatory diseases or cancers. The CAS number 1610761-46-0 uniquely identifies this chemical substance, facilitating its recognition in scientific literature and regulatory contexts. Overall, this antibody exemplifies the intersection of immunology and biochemistry, showcasing the potential for targeted therapies in modern medicine.

Immunoglobulin G1, anti-(human CC chemokine receptor CCR2) (human-Mus musculus monoclonal 1D9 heavy chain), disulfide with human-Mus musculus monoclonal 1D9 κ-chain, dimer

1610761-46-0: Immunoglobulin G1 (IgG1) is a type of antibody that plays a crucial role in the immune response by recognizing and binding to specific antigens. The substance in question is a monoclonal antibody targeting the human CC chemokine receptor CCR2, which is involved in immune cell signaling and inflammation. This particular antibody is a dimer, meaning it consists of two identical units linked by disulfide bonds, enhancing its stability and functionality. The heavy chain is derived from a mouse (Mus musculus) source, while the kappa chain is also of murine origin, indicating its hybridoma technology-based production. The specificity for CCR2 suggests potential applications in therapeutic interventions for conditions involving this receptor, such as certain inflammatory diseases or cancers. The CAS number 1610761-46-0 uniquely identifies this chemical substance, facilitating its recognition in scientific literature and regulatory contexts. Overall, this antibody exemplifies the intersection of immunology and biochemistry, showcasing the potential for targeted therapies in modern medicine.

<p>Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of</p>

Plozalizumab

<p>Anti-CCR2 humanized monoclonal antibody</p>

CAS 1610761-46-0

Immunoglobulin G1, anti-(human CC chemokine receptor CCR2) (human-Mus musculus monoclonal 1D9 heavy chain), disulfide with human-Mus musculus monoclonal 1D9 κ-chain, dimer

Plozalizumab

Ref: TM-T77118

Plozalizumab

Ref: 3D-CLA1402