CAS 16110-13-7

Benz[a]anthracene-7-methanol

Description:

Benz[a]anthracene-7-methanol is a polycyclic aromatic hydrocarbon (PAH) derivative characterized by the presence of a hydroxymethyl group at the 7-position of the benz[a]anthracene structure. This compound is typically a solid at room temperature and exhibits a high degree of hydrophobicity due to its extensive aromatic system. It is known for its potential mutagenic and carcinogenic properties, which are common among many PAHs. The presence of the hydroxymethyl group can influence its reactivity and solubility compared to its parent compound, benz[a]anthracene. In terms of applications, it may be used in research settings to study the behavior of PAHs in biological systems or environmental contexts. Safety precautions are essential when handling this compound, as it may pose health risks upon exposure. Overall, Benz[a]anthracene-7-methanol serves as an important compound in the study of organic chemistry, toxicology, and environmental science.

Formula: C₁₉H₁₄O

InChI: InChI=1S/C19H14O/c20-12-19-16-8-4-2-6-14(16)11-18-15-7-3-1-5-13(15)9-10-17(18)19/h1-11,20H,12H2

InChI key: InChIKey=FWFOOWHDKQMDKI-UHFFFAOYSA-N

SMILES: C(O)C=1C=2C(=C3C(=CC2)C=CC=C3)C=C4C1C=CC=C4

Synonyms:

• 10-Hydroxymethyl-1,2-benzanthracene
• 7-(Hydroxymethyl)benz[a]anthracene
• 7-Hmba
• Benz(a)anthracene-7-methanol
• Brn 1882113
• Ccris 2361
• Tetraphen-7-Ylmethanol
• 7-Hydroxymethylbenz(a)anthracene
• 4-06-00-05088 (Beilstein Handbook Reference)

Benz[a]anthracene-7-methanol

CAS: 16110-13-7

Formula: C₁₉H₁₄O

Color and Shape: Solid

Molecular weight: 258.3139

Ref: IN-DA001S6K

Benz[a]anthracene-7-methanol

Controlled Product

CAS: 16110-13-7

Applications Metabolite of formyl-substituted benzanthracenes.
References Horn, J. et al.; Chem-Biol. Interact. 145, 17 (2003)

Formula: C₁₉H₁₄O

Color and Shape: Neat

Molecular weight: 258.31

Ref: TR-B183605

Benz[A]anthracene-7-methanol

CAS: 16110-13-7

Benz[A]anthracene-7-methanol is a cytosolic carcinogen that is metabolized by the liver to form benz[a]anthracene-7,8-epoxide. This metabolite binds to DNA and causes mutations in the genes, which leads to cancer. The hydroxyl group of this compound reacts with epidermal growth factor, causing an increase in the number of liver cells that can cause cancer. Benz[A]anthracene-7-methanol also interacts with reactive oxygen species and stimulates the production of growth factors like epidermal growth factor, which promote skin cell growth. It has been shown that benz[A]anthracene-7-methanol promotes tumorigenesis in CD1 mice and induces tumor formation in rat liver microsomes.

Formula: C₁₉H₁₄O

Purity: Min. 95%

Molecular weight: 258.3 g/mol

Ref: 3D-RAA11013