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CAS 161110-05-0

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3'-Deoxy-5'-O-trityl-D-uridine

Description:
3'-Deoxy-5'-O-trityl-D-uridine is a modified nucleoside that plays a significant role in biochemical research and synthetic chemistry, particularly in the field of oligonucleotide synthesis. This compound features a uridine base, which is a nucleoside composed of a pyrimidine ring (uracil) linked to a ribose sugar. The "3'-deoxy" modification indicates the absence of a hydroxyl group at the 3' position of the sugar, which enhances its stability and resistance to enzymatic degradation. The "5'-O-trityl" designation refers to the presence of a trityl protecting group at the 5' position, which is commonly used to protect the hydroxyl group during chemical reactions. This modification allows for selective reactions at other positions of the nucleoside. Overall, 3'-Deoxy-5'-O-trityl-D-uridine is utilized in the synthesis of oligonucleotides and other nucleic acid derivatives, facilitating the study of nucleic acid interactions and functions in various biological contexts.
Formula:C28H26N2O5
InChI:InChI=1S/C28H26N2O5/c31-24-18-23(35-26(24)30-17-16-25(32)29-27(30)33)19-34-28(20-10-4-1-5-11-20,21-12-6-2-7-13-21)22-14-8-3-9-15-22/h1-17,23-24,26,31H,18-19H2,(H,29,32,33)/t23-,24+,26+/m0/s1
InChI key:InChIKey=SERBFLXSXXCIFH-BFLUCZKCSA-N
SMILES:C(OC[C@H]1O[C@H]([C@H](O)C1)N2C(=O)NC(=O)C=C2)(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5
Synonyms:
  • Uridine, 3′-deoxy-5′-O-(triphenylmethyl)-
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Found 3 products.
  • Uridine, 3′-deoxy-5′-O-(triphenylmethyl)-
    Indagoo
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    Uridine, 3′-deoxy-5′-O-(triphenylmethyl)-

    CAS:
    Formula:C28H26N2O5
    Color and Shape:Solid
    Molecular weight:470.5164

    Ref: IN-DA001S67

    ne
    To inquire
  • 3''-Deoxy-5''-O-trityluridine
    Glentham
    + Info

    3''-Deoxy-5''-O-trityluridine

    CAS:

    Ref: 7W-GN7031

    ne
    To inquire
  • 3'-Deoxy-5'-O-trityluridine
    Biosynth
    + Info

    3'-Deoxy-5'-O-trityluridine

    CAS:
    <p>3'-Deoxy-5'-O-trityluridine is a nucleoside that is structurally related to uridine. It belongs to the class of nucleosides and has a hydroxyl group at the 3' position. The 5' position is modified by an anion (most often trityl) sterically, which prevents hydrolysis by esterases or phosphatases. The efficiency of this modification can be increased by using diethyl phosphate as the protecting agent. This modification also provides protection against nucleophiles, such as hydroxyl groups in nucleosides or phosphite triester derivatives. 3'-Deoxy-5'-O-trityluridine is used in the synthesis of other nucleosides and as a substrate for diffraction experiments.</p>
    Formula:C28H26N2O5
    Purity:Min. 95%
    Molecular weight:470.53 g/mol

    Ref: 3D-ND05370

    25mg
    303.00€
    50mg
    365.00€