CAS 161115-59-9
:Desisobutyryl-ciclesonide
Description:
Desisobutyryl-ciclesonide is a synthetic corticosteroid primarily used for its anti-inflammatory properties. It is a derivative of ciclesonide, which is known for its effectiveness in treating respiratory conditions such as asthma and allergic rhinitis. The compound exhibits a high affinity for glucocorticoid receptors, leading to potent anti-inflammatory effects while minimizing systemic side effects. Desisobutyryl-ciclesonide is characterized by its lipophilicity, which enhances its local action in the lungs when administered via inhalation. Its pharmacokinetics involve rapid metabolism and clearance, contributing to a favorable safety profile. The substance is typically formulated as an aerosol or inhalation powder, allowing for targeted delivery to the respiratory tract. Additionally, it is important to note that the compound's efficacy is influenced by factors such as dosage, administration technique, and patient adherence to treatment regimens. Overall, desisobutyryl-ciclesonide represents a significant advancement in the management of chronic respiratory diseases, providing relief from inflammation with a reduced risk of adverse effects.
Formula:C28H38O6
InChI:InChI=1S/C28H38O6/c1-26-11-10-18(30)12-17(26)8-9-19-20-13-23-28(22(32)15-29,27(20,2)14-21(31)24(19)26)34-25(33-23)16-6-4-3-5-7-16/h10-12,16,19-21,23-25,29,31H,3-9,13-15H2,1-2H3/t19-,20-,21-,23+,24+,25+,26-,27-,28+/m0/s1
InChI key:InChIKey=OXPLANUPKBHPMS-ZXBNPROVSA-N
SMILES:C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@H](O2)[C@@H]4CCCCC4)[H])([C@]5([C@]([C@@H](O)C3)([C@]6(C)C(CC5)=CC(=O)C=C6)[H])[H])[H]
Synonyms:- CIC-AP
- Pregna-1,4-diene-3,20-dione, 16,17-[(cyclohexylmethylene)bis(oxy)]-11,21-dihydroxy-, [11β,16α(R)]-
- Ciclesonide active principle
- Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-
- (11β,16α)-16,17-[[(R)-Cyclohexylmethylene]bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
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Found 8 products.
Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-
CAS:Formula:C28H38O6Purity:95%Color and Shape:SolidMolecular weight:470.5977Ciclesonide-desisobutyryl
CAS:Controlled ProductFormula:C28H38O6Color and Shape:NeatMolecular weight:470.60Desisobutyryl Ciclesonide
CAS:Controlled Product<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formula:C28H38O6Color and Shape:White To Off-WhiteMolecular weight:470.60Desisobutyryl-ciclesonide
CAS:<p>Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide with affinity for the glucocorticoid receptor. a glucocorticoid with anti-inflammatory.</p>Formula:C28H38O6Purity:98%Color and Shape:SolidMolecular weight:470.6
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