CAS 161115-59-9: Desisobutyryl-ciclesonide

Description: Desisobutyryl-ciclesonide is a synthetic corticosteroid primarily used for its anti-inflammatory properties. It is a derivative of ciclesonide, which is known for its effectiveness in treating respiratory conditions such as asthma and allergic rhinitis. The compound exhibits a high affinity for glucocorticoid receptors, leading to potent anti-inflammatory effects while minimizing systemic side effects. Desisobutyryl-ciclesonide is characterized by its lipophilicity, which enhances its local action in the lungs when administered via inhalation. Its pharmacokinetics involve rapid metabolism and clearance, contributing to a favorable safety profile. The substance is typically formulated as an aerosol or inhalation powder, allowing for targeted delivery to the respiratory tract. Additionally, it is important to note that the compound's efficacy is influenced by factors such as dosage, administration technique, and patient adherence to treatment regimens. Overall, desisobutyryl-ciclesonide represents a significant advancement in the management of chronic respiratory diseases, providing relief from inflammation with a reduced risk of adverse effects.

Formula: C₂₈H₃₈O₆

InChI: InChI=1S/C28H38O6/c1-26-11-10-18(30)12-17(26)8-9-19-20-13-23-28(22(32)15-29,27(20,2)14-21(31)24(19)26)34-25(33-23)16-6-4-3-5-7-16/h10-12,16,19-21,23-25,29,31H,3-9,13-15H2,1-2H3/t19-,20-,21-,23+,24+,25+,26-,27-,28+/m0/s1

InChI key: InChIKey=OXPLANUPKBHPMS-ZXBNPROVSA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CC5OC(OC5(C(=O)CO)C4(C)CC(O)C32)C6CCCCC6)C

Synonyms:

• CIC-AP
• Pregna-1,4-diene-3,20-dione, 16,17-[(cyclohexylmethylene)bis(oxy)]-11,21-dihydroxy-, [11β,16α(R)]-
• Ciclesonide active principle
• Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-
• (11β,16α)-16,17-[[(R)-Cyclohexylmethylene]bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

Ciclesonide impurity B CRS

CAS: 161115-59-9

• Formula: C₂₈H₃₈O₆

Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-

CAS: 161115-59-9

• Formula: C₂₈H₃₈O₆
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 470.5977

Ciclesonide EP Impurity B (21-Desisobutyryl Ciclesonide)

CAS: 161115-59-9

• Formula: C₂₈H₃₈O₆
• Molecular weight: 470.61

Ciclesonide-desisobutyryl

CAS: 161115-59-9

• Formula: C₂₈H₃₈O₆
• Color and Shape: Neat
• Molecular weight: 470.60

Desisobutyryl Ciclesonide

CAS: 161115-59-9

Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma. References Austin, …

• Formula: C₂₈H₃₈O₆
• Color and Shape: White To Off-White
• Molecular weight: 470.60

Desisobutyryl-ciclesonide

CAS: 161115-59-9

Desisobutyryl-ciclesonide has an affinity for glucocorticoid receptors. Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide.

• Formula: C₂₈H₃₈O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 470.6

Desisobutyryl ciclesonide

CAS: 161115-59-9

Desisobutyryl ciclesonide is a prodrug of ciclesonide, which is a potent and specific beta-adrenergic agonist. …

• Formula: C₂₈H₃₈O₆
• Purity: Min. 95%
• Molecular weight: 470.6 g/mol