![(2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F307254-bictegravir.webp&w=3840&q=75)
CAS 1611493-60-7
:(2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
Description:
The chemical substance with the name "(2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide" and CAS number "1611493-60-7" is a complex organic compound characterized by its multi-cyclic structure, which includes a pyrido-pyrazino framework and an oxazepine moiety. This compound features multiple functional groups, including hydroxyl, carbonyl, and amide groups, contributing to its potential biological activity. The presence of a trifluorophenyl substituent suggests enhanced lipophilicity and possibly increased potency in biological systems. The stereochemistry indicated by the (2R,5S,13aR) configuration suggests specific spatial arrangements that may influence the compound's interactions with biological targets. Such compounds are often investigated for their pharmacological properties, including potential therapeutic applications in various medical fields. Overall, the structural complexity and functional diversity of this substance make it a subject of interest in medicinal chemistry and drug development.
Formula:C21H18F3N3O5
InChI:InChI=1S/C21H18F3N3O5/c22-9-3-14(23)12(15(24)4-9)6-25-20(30)13-7-26-8-16-27(10-1-2-11(5-10)32-16)21(31)17(26)19(29)18(13)28/h3-4,7,10-11,16,29H,1-2,5-6,8H2,(H,25,30)/t10-,11+,16+/m0/s1
InChI key:InChIKey=SOLUWJRYJLAZCX-LYOVBCGYSA-N
SMILES:O=C1N2[C@@](CN3C1=C(O)C(=O)C(C(NCC4=C(F)C=C(F)C=C4F)=O)=C3)(O[C@]5(C[C@@]2(CC5)[H])[H])[H]
Synonyms:- (2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
- (2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
- (2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
- 2,5-Methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide, 2,3,4,5,7,9,13,13a-octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-(2R,5S,13aR)
- 2,5-Methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide, 2,3,4,5,7,9,13,13a-octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-, (2R,5S,13aR)-
- Gs 9883
- Bictegravir
- Bictegravir (GS-9883)
- Bictegravin
- (2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)
- BICTEGRAVIR;GS-9883;GS 9883;GS9883
- Bictegravir (100 mg/mL in DMSO)
- See more synonyms
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Found 12 products.
(2R,5S,13Ar)-8-Hydroxy-7,9-Dioxo-N-(2,4,6-Trifluorobenzyl)-2,3,4,5,7,9,13,13A-Octahydro-2,5-Methanopyrido[1',2':4,5]Pyrazino[2,1-b][1,3]Oxazepine-10-Carboxamide
CAS:(2R,5S,13Ar)-8-Hydroxy-7,9-Dioxo-N-(2,4,6-Trifluorobenzyl)-2,3,4,5,7,9,13,13A-Octahydro-2,5-Methanopyrido[1',2':4,5]Pyrazino[2,1-b][1,3]Oxazepine-10-CarboxamidePurity:98%Molecular weight:449.38g/molBictegravir
CAS:Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).Formula:C21H18F3N3O5Purity:97.6% - 99.51%Color and Shape:SolidMolecular weight:449.38Bictegravir
CAS:Controlled Product<p>Applications Bictegravir, is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.<br>References Tsiang M. et al.: Antimicrob Agents Chemother. 2016 Nov 21;60(12):7086-7097;<br></p>Formula:C21H18F3N3O5Color and Shape:White To Off-WhiteMolecular weight:449.3799Bictegravir-15N, d2
CAS:Controlled Product<p>Applications Bictegravir-15N, d2 is the labeled version of Bictegravir, which is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.<br>References Tsiang M. et al.: Antimicrob Agents Chemother. 2016 Nov 21;60(12):7086-7097;<br></p>Formula:C212H2H16F315NN2O5Color and Shape:NeatMolecular weight:452.39Bictegravir
CAS:<p>Inhibitor of HIV-1 integrase strand transfer; antiviral</p>Formula:C21H18F3N3O5Purity:Min. 95%Color and Shape:Off-White To Yellow To Orange Or Light Brown SolidMolecular weight:449.38 g/molBictegravir-d6
CAS:Controlled ProductFormula:C21D6H12F3N3O5Color and Shape:NeatMolecular weight:455.417Bictegravir (100 mg/mL in DMSO)
CAS:Controlled ProductFormula:C21H18F3N3O5Color and Shape:Single SolutionMolecular weight:449.3799
