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CAS 1612191-87-3

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3′-Deoxy-3′-fluoroinosine oxime

Description:
3′-Deoxy-3′-fluoroinosine oxime is a synthetic compound that belongs to the class of nucleoside analogs, specifically modified derivatives of inosine. Its structure features a fluorine atom substituted at the 3′ position of the ribose sugar, which alters its biochemical properties and potential interactions with nucleic acid synthesis pathways. The oxime functional group introduces a nitrogen-oxygen double bond, which can influence the compound's reactivity and stability. This modification may enhance its affinity for certain enzymes or receptors, making it a candidate for research in antiviral or anticancer therapies. The presence of the fluorine atom can also affect the compound's lipophilicity and bioavailability. As a nucleoside analog, it may interfere with nucleic acid metabolism, potentially leading to inhibition of viral replication or modulation of cellular processes. Overall, 3′-Deoxy-3′-fluoroinosine oxime represents a valuable tool in medicinal chemistry and pharmacology, with ongoing studies to elucidate its full therapeutic potential and mechanisms of action.
Formula:C10H12FN5O4
InChI:InChI=1S/C10H12FN5O4/c11-5-4(1-17)20-10(7(5)18)16-3-14-6-8(15-19)12-2-13-9(6)16/h2-5,7,10,17-19H,1H2,(H,12,13,15)/t4-,5-,7-,10-/m1/s1
InChI key:InChIKey=KHVVBEAFTGEGFT-QYYRPYCUSA-N
SMILES:O[C@H]1[C@H](N2C3=C(N=C2)C(=NO)N=CN3)O[C@H](CO)[C@H]1F
Synonyms:
  • 3′-Deoxy-3′-fluoroinosine oxime
  • Inosine, 3′-deoxy-3′-fluoro-, oxime
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Found 1 products.
  • 3’-Deoxy-3’-fluoro-N6-hydroxyadenosine
    Biosynth
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    3’-Deoxy-3’-fluoro-N6-hydroxyadenosine

    CAS:
    3’-Deoxy-3’-fluoro-N6-hydroxyadenosine (3'-DF) is an antiviral nucleoside that inhibits viral DNA synthesis and has shown cytotoxic effects in human cancer cells. 3'-DF is a novel chemical compound that was first synthesized in 1994. It is a nucleotide analog that is structurally related to adenosine, with the exception of the fluoro atom at position 6 on the ribose sugar. 3'-DF inhibits DNA polymerase and RNA polymerase by competitively binding to the ribonucleotide reductase enzyme, inhibiting the production of new RNA and DNA molecules. This compound also has been shown to inhibit protein synthesis in cancer cells without affecting normal cells.
    Purity:Min. 95%

    Ref: 3D-ND162841

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