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CAS 1612191-90-8

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9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-9H-purine

Description:
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-9H-purine is a synthetic nucleoside analog characterized by its unique structural features, which include a purine base and a modified ribofuranosyl sugar. The presence of a 3-deoxy-3-fluoro group on the ribose ring enhances its stability and may influence its biological activity, making it a subject of interest in medicinal chemistry, particularly in antiviral and anticancer research. The thienyl group at the 6-position of the purine ring contributes to its lipophilicity and potential interactions with biological targets. This compound may exhibit properties such as altered binding affinity to nucleic acid structures or enzymes involved in nucleic acid metabolism. Its specific interactions and efficacy would depend on the context of its application, including the type of biological system being studied. Overall, this compound represents a class of modified nucleosides that can provide insights into nucleic acid function and therapeutic potential.
Formula:C14H13FN4O3S
InChI:InChI=1S/C14H13FN4O3S/c15-9-8(3-20)22-14(12(9)21)19-6-18-11-10(7-1-2-23-4-7)16-5-17-13(11)19/h1-2,4-6,8-9,12,14,20-21H,3H2/t8-,9-,12-,14-/m1/s1
InChI key:InChIKey=JJUMGDXEERDGDF-ULSKOJAOSA-N
SMILES:O[C@H]1[C@H](N2C=3C(=C(N=CN3)C=4C=CSC4)N=C2)O[C@H](CO)[C@H]1F
Synonyms:
  • 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-
  • 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-9H-purine
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Found 2 products.
  • 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(thiophen-3-yl)purine
    Targetmol
    + Info

    9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(thiophen-3-yl)purine

    CAS:
    <p>9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(thiophen-3-yl)purine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, 3'-</p>
    Formula:C14H13FN4O3S
    Color and Shape:Solid
    Molecular weight:336.34

    Ref: TM-TNU0063

  • 9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-(thiophen-3-yl)purine
    Biosynth
    + Info

    9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-(thiophen-3-yl)purine

    CAS:
    <p>9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-(thiophen-3-yl)purine is a novel monophosphate nucleotide analog, which has been shown to be an activator of anticancer activity. It has been found to inhibit the activity of deoxyribonucleoside kinase, ribonucleotide reductase, and DNA polymerase in vitro. 9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-(thiophen-3-yl)purine is not a substrate for nucleoside phosphorylase and is not incorporated into DNA or RNA. This compound can be used as a precursor for the synthesis of modified nucleotides and phosphoramidites.</p>
    Purity:Min. 95%

    Ref: 3D-ND162836

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