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CAS 1612192-05-8

:

6-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine

Description:
6-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine derivative characterized by the presence of a chlorine atom at the 6-position and a modified ribofuranosyl moiety at the 9-position. This compound features a fluorine substitution at the 3-deoxy position of the ribose sugar, which can influence its biological activity and stability. The purine base structure contributes to its potential role in nucleic acid metabolism and as a building block for nucleotides. The presence of the chlorine and fluorine atoms may enhance its lipophilicity and alter its interaction with biological targets, making it of interest in medicinal chemistry, particularly in the development of antiviral or anticancer agents. Its unique structural features may also affect its solubility, reactivity, and pharmacokinetic properties. Overall, this compound represents a significant modification of traditional purine structures, potentially leading to novel therapeutic applications.
Formula:C10H11ClFN5O3
InChI:InChI=1S/C10H11ClFN5O3/c11-7-5-8(16-10(13)15-7)17(2-14-5)9-6(19)4(12)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4-,6-,9-/m1/s1
InChI key:InChIKey=QDMZZCZDGYVCCS-DXTOWSMRSA-N
SMILES:ClC1=C2C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](F)[C@H]3O)=NC(N)=N1
Synonyms:
  • 6-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine
  • 9H-Purin-2-amine, 6-chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-
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Found 2 products.
  • 2-Amino-6-chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purine

    CAS:
    2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - Fluoro-modified nucleoside, Halo-nucleoside, 3'-Modified
    Formula:C10H11ClFN5O3
    Color and Shape:Solid
    Molecular weight:303.68

    Ref: TM-TNU0090

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  • 2-Amino-6-chloro-9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-9H-purine

    CAS:
    2-Amino-6-chloro-9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-9H-purine is a novel, activator ribonucleoside phosphoramidite and monophosphate nucleoside. It is synthesized from 2,4,5,6,-tetraiodo-1H-[1]pyrrole and 6-chloropurine ribofuranose. The chemical name is 1-[2'-(deoxyribofuranosyl) (3', 3'', 5', 5'', 5'')-2'-(2,4,5,6 tetraiodophenyl)] -2-(3'-fluorobenzoyl) -4-(3'-triazolecarboxamide) -1H-[1]pyrrole 4,5 dione. CAS No. 1612192-05-8.
    Purity:Min. 95%

    Ref: 3D-NA162845

    100mg
    1,250.00€