CAS 161308-39-0
:A,B-methyleneguanosine 5'-diphosphate,*sodium
Description:
A,B-Methyleneguanosine 5'-diphosphate, sodium salt, is a synthetic nucleotide analog characterized by its unique structure that includes a methylene bridge at the A and B positions of the guanosine moiety. This modification enhances its stability and resistance to hydrolysis compared to natural nucleotides. The compound typically exists as a sodium salt, which aids in its solubility in aqueous solutions, making it suitable for various biochemical applications. It plays a significant role in studies related to nucleotide signaling pathways and enzyme interactions, particularly in the context of GTP-binding proteins. The presence of the diphosphate group allows it to participate in phosphorylation reactions, mimicking the behavior of natural nucleotides. Its applications extend to research in molecular biology, biochemistry, and pharmacology, where it can serve as a tool for investigating cellular processes and potential therapeutic targets. Overall, A,B-methyleneguanosine 5'-diphosphate, sodium salt, is a valuable compound in the study of nucleotide function and signaling mechanisms.
Formula:C11H17N5O10P2
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
α,β-Methyleneguanosine 5′-diphosphate sodium salt
CAS:Formula:C11H17N5O10P2·xNaMolecular weight:441.23 (free acid ba,b-Methyleneguanosine 5'-diphosphate sodium salt
CAS:<p>a,b-Methyleneguanosine 5'-diphosphate sodium salt is a chemical species that binds to the influenza virus neuraminidase. The drug binding site on the influenza virus neuraminidase has been identified in high resolution by NMR and X-ray crystallography. This drug is able to inhibit the release of infectious particles and prevent infection by the influenza virus, which is an important biological weapon in bioterrorism. The compound is not active against other viruses such as HIV and herpes simplex virus type 1. In addition, this chemical species also inhibits the activity of geniculate nucleus neurons and may be effective for treatment of chronic pain caused by nerve injury.</p>Formula:C11H17N5O10P2·xNaPurity:Min. 95%Molecular weight:441.23 g/mol

