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CAS 1613220-15-7

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Niraparib TsOH

Description:
Niraparib TsOH, with the CAS number 1613220-15-7, is a chemical compound that serves as a potent inhibitor of poly(ADP-ribose) polymerase (PARP), primarily used in cancer therapy. It is a derivative of Niraparib, which is known for its application in treating certain types of ovarian and breast cancers, particularly in patients with BRCA mutations. The "TsOH" indicates the presence of a tosyl group, which can enhance the compound's solubility and stability. Niraparib TsOH exhibits characteristics typical of PARP inhibitors, including the ability to interfere with DNA repair mechanisms in cancer cells, leading to increased cell death. Its pharmacological profile includes oral bioavailability and a favorable half-life, making it suitable for chronic administration in clinical settings. Additionally, the compound is subject to ongoing research to better understand its efficacy, safety, and potential side effects in various cancer types. As with many pharmaceuticals, its use is accompanied by monitoring for adverse reactions and interactions with other medications.
Synonyms:
  • Niraparib tosylate hydrate
  • Niraparib TOS H2O
  • Nilapani toluene monohydrate
  • (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate hydrate
  • Niraparib TsOH salt hydrate
  • Niraparib tosylate
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Found 6 products.