Teixobactin is a novel antibiotic that was discovered in 2015 and is notable for its effectiveness against a range of Gram-positive bacteria, including drug-resistant strains such as MRSA. It is a cyclic lipopeptide, characterized by a unique mechanism of action that involves binding to lipid II and lipid III, essential components in bacterial cell wall synthesis. This binding disrupts the formation of the cell wall, leading to bacterial cell death. Teixobactin is derived from a previously uncultured bacterium found in soil, highlighting the potential of environmental microorganisms as sources of new antibiotics. Its stability and low toxicity in mammalian cells make it a promising candidate for therapeutic use. However, research is ongoing to fully understand its pharmacokinetics, potential resistance mechanisms, and efficacy in clinical settings. As of now, teixobactin represents a significant advancement in the search for new antibiotics in the face of rising antibiotic resistance.

teixobactin

1613225-53-8: Teixobactin is a novel antibiotic that was discovered in 2015 and is notable for its effectiveness against a range of Gram-positive bacteria, including drug-resistant strains such as MRSA. It is a cyclic lipopeptide, characterized by a unique mechanism of action that involves binding to lipid II and lipid III, essential components in bacterial cell wall synthesis. This binding disrupts the formation of the cell wall, leading to bacterial cell death. Teixobactin is derived from a previously uncultured bacterium found in soil, highlighting the potential of environmental microorganisms as sources of new antibiotics. Its stability and low toxicity in mammalian cells make it a promising candidate for therapeutic use. However, research is ongoing to fully understand its pharmacokinetics, potential resistance mechanisms, and efficacy in clinical settings. As of now, teixobactin represents a significant advancement in the search for new antibiotics in the face of rising antibiotic resistance.

Teixobactin is a recently described antibiotic .

CAS 1613225-53-8

teixobactin

Teixobactin

Ref: TM-T26257