CAS 161383-47-7

Adrenomedullin (rat)(9CI)

Description:

Adrenomedullin (rat) is a peptide that plays a significant role in various physiological processes, including vasodilation, regulation of blood pressure, and modulation of inflammatory responses. It is a 52-amino acid peptide originally isolated from rat pheochromocytoma cells and is part of the calcitonin gene-related peptide (CGRP) family. The substance is known for its potent vasodilatory effects, which are mediated through the activation of specific receptors, leading to increased intracellular cyclic AMP levels. Adrenomedullin is also involved in the regulation of cardiovascular functions and has been implicated in various pathological conditions, including heart failure and sepsis. Its structure includes a characteristic ring formed by a disulfide bond, which is crucial for its biological activity. The CAS number 161383-47-7 uniquely identifies this compound, facilitating its recognition in scientific literature and databases. Overall, adrenomedullin is an important biomolecule with diverse roles in health and disease, making it a subject of interest in pharmacological and biomedical research.

Formula: C₂₄₂H₃₈₀N₇₆O₇₆S₅

Synonyms:

• L-Tyrosinamide,L-tyrosyl-L-arginyl-L-glutaminyl-L-seryl-L-methionyl-L-asparaginyl-L-glutaminylglycyl-L-seryl-L-arginyl-L-seryl-L-threonylglycyl-L-cysteinyl-L-arginyl-L-phenylalanylglycyl-L-threonyl-L-cysteinyl-L-threonyl-L-methionyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-L-phenylalanyl-L-threonyl-L-a-aspartyl-L-lysyl-L-a-aspartyl-L-lysyl-L-a-aspartylglycyl-L-methionyl-L-alanyl-L-prolyl-L-arginyl-L-asparaginyl-L-lysyl-L-isoleucyl-L-seryl-L-prolyl-L-glutaminylglycyl-,cyclic (14® 19)-disulfide
• Ratadrenomedullin
• Rat adrenomedullin(1-50)

Adrenomedullin (rat)

CAS: 161383-47-7

Synthetic rat adrenomedullin (rADM) elicits a potent and longlasting hypotensive activity in anesthesized rats.

Formula: C₂₄₂H₃₈₁N₇₇O₇₅S₅

Purity: ≥ 97%

Color and Shape: White

Molecular weight: 5729.49

Ref: 01-4030175

Adrenomedullin (rat)

CAS: 161383-47-7

Adrenomedullin (rat), a potent vasodilator peptide, is secreted by both endothelial cells (EC) and vascular smooth muscle cells (VSMC) [1].

Color and Shape: Solid

Ref: TM-T83163

Adrenomedullin (rat) trifluoroacetate salt

CAS: 161383-47-7

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Formula: C₂₄₂H₃₈₁N₇₇O₇₅S₅

Purity: Min. 95%

Molecular weight: 5,729.42 g/mol

Ref: 3D-FA108808