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CAS 161397-68-8

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1H-Indole-5-carbonyl chloride (9CI)

Description:
1H-Indole-5-carbonyl chloride, also known by its CAS number 161397-68-8, is an organic compound characterized by the presence of an indole ring system, which is a bicyclic structure consisting of a benzene ring fused to a pyrrole ring. This compound features a carbonyl chloride functional group (-C(=O)Cl) at the 5-position of the indole, making it a reactive acyl chloride. It is typically used as an intermediate in organic synthesis, particularly in the preparation of various indole derivatives and pharmaceuticals. The presence of the carbonyl chloride group enhances its reactivity, allowing it to participate in nucleophilic acyl substitution reactions. 1H-Indole-5-carbonyl chloride is generally a colorless to pale yellow liquid or solid, depending on its purity and storage conditions. It should be handled with care due to its potential to release hydrochloric acid upon hydrolysis and its reactivity with water and alcohols. Proper safety precautions, including the use of personal protective equipment, are essential when working with this compound.
Formula:C9H6ClNO
Synonyms:
  • 1H-Indole-5-carbonyl chloride
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