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CAS 161420-87-7

:

Fmoc-Dab-OH

Description:
Fmoc-Dab-OH, or 9-fluorenylmethoxycarbonyl-2,3-diaminobutyric acid, is a protected amino acid commonly used in peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amine functionality, allowing for selective reactions during peptide assembly. The presence of the 2,3-diaminobutyric acid (Dab) moiety introduces two amino groups, enhancing its utility in creating diverse peptide structures. Fmoc-Dab-OH is typically soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane, while being less soluble in water. Its stability under basic conditions makes it suitable for solid-phase peptide synthesis, where the Fmoc group can be easily removed under mild basic conditions, facilitating the sequential addition of amino acids. The compound is characterized by its ability to form stable peptide bonds and is often utilized in the development of bioactive peptides and pharmaceuticals. Proper handling and storage are essential, as with many chemical substances, to maintain its integrity and reactivity.
Formula:C19H20N2O4
Synonyms:
  • Fmoc-Dab
  • Fmoc-Dab-Oh Hcl
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