CAS 161442-19-9

2'-Fluoro-N4-Benzoyl-5'-O-DMT-2'-deoxycytidine-3'-CE-Phosphoramidite

Description:

2'-Fluoro-N4-Benzoyl-5'-O-DMT-2'-deoxycytidine-3'-CE-Phosphoramidite is a modified nucleoside analog used primarily in the field of oligonucleotide synthesis. This compound features a 2'-fluoro modification, which enhances the stability and binding affinity of the nucleoside, making it particularly useful in the development of antisense oligonucleotides and RNA interference applications. The presence of a benzoyl group at the N4 position of the cytidine base contributes to its solubility and reactivity, while the 5'-O-DMT (dimethoxytrityl) protecting group allows for selective deprotection during synthesis. The CE (cyanoethyl) phosphoramidite moiety is crucial for the incorporation of this nucleoside into growing oligonucleotide chains through phosphoramidite chemistry. Overall, this compound is characterized by its enhanced stability, reactivity, and utility in the synthesis of modified nucleic acids, making it a valuable tool in molecular biology and therapeutic development.

Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS: 161442-19-9

Formula: C₄₆H₅₁FN₅O₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 851.8980

Ref: IN-DA001SH9

(2R,3R,4R,5R)-5-(4-Benzamido-2-Oxopyrimidin-1(2H)-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Fluorotetrahydrofuran-3-Yl (2-Cyanoethyl) Diisopropylphosphoramidite

CAS: 161442-19-9

(2R,3R,4R,5R)-5-(4-Benzamido-2-Oxopyrimidin-1(2H)-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Fluorotetrahydrofuran-3-Yl (2-Cyanoethyl) Diisopropylphosphoramidite

Purity: 98%

Molecular weight: 851.9g/mol

Ref: 54-PC109908

N4-Benzoyl-2''-deoxy-5''-O-DMT-2''-fluoro-cytidine phosphoramidite

CAS: 161442-19-9

Ref: 7W-GN2242

DMT-2'-Fluoro-dC(Bz) Phosphoramidite

CAS: 161442-19-9

Formula: C₄₆H₅₁FN₅O₈P

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 851.91

Ref: 3B-D5943

N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine 3-CE phosphoramidite

CAS: 161442-19-9

N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine 3-CE phosphoramidite is a novel nucleoside phosphoramidite that is used for the synthesis of DNA and RNA. It has anticancer properties and has been shown to inhibit the replication of HIV and herpes virus. N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine 3-CE phosphoramidite is also a potent antiviral that inhibits the production of diphosphate by inhibiting ribonucleotide reductase, an enzyme involved in DNA synthesis.

Formula: C₄₆H₅₁FN₅O₈P

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 851.9 g/mol

Ref: 3D-PB15179

2′-F-Bz-dC Phosphoramidite

CAS: 161442-19-9

Purity: 98%

Molecular weight: 851.913

Ref: 10-F987430