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CAS 161525-56-0

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2-(Difluoromethyl)benzenesulfonyl chloride

Description:
2-(Difluoromethyl)benzenesulfonyl chloride is an organosulfur compound characterized by the presence of a sulfonyl chloride functional group attached to a benzene ring that also features a difluoromethyl substituent. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity, particularly due to the sulfonyl chloride group, which can undergo nucleophilic substitution reactions. The difluoromethyl group enhances its electrophilic character, making it useful in various synthetic applications, including the preparation of pharmaceuticals and agrochemicals. It is important to handle this compound with care, as it can be corrosive and may pose health hazards upon exposure. Additionally, it is soluble in organic solvents, which facilitates its use in organic synthesis. As with many sulfonyl chlorides, it can react with water, releasing hydrochloric acid and forming the corresponding sulfonic acid, which underscores the need for proper storage and handling protocols to prevent unwanted reactions.
Formula:C7H5ClF2O2S
InChI:InChI=1S/C7H5ClF2O2S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4,7H
InChI key:InChIKey=HOHYZHBHYKDMAT-UHFFFAOYSA-N
SMILES:S(Cl)(=O)(=O)C1=C(C(F)F)C=CC=C1
Synonyms:
  • 2-(Difluoromethyl)benzenesulfonyl chloride
  • Benzenesulfonyl chloride, 2-(difluoromethyl)-
  • 2-(Difluoromethyl)benzene-1-sulfonyl chloride
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