CAS 161552-03-0

Cyclo(-Arg-Gly-Asp-D-Phe-Lys)

CAS: 161552-03-0

An RGD tumor-targeting peptide, which binds to αvβ3 receptors. c(RGDfK) can be easily conjugated to fluorophore tags, chelators, or carriers. Palecek et al. converted the ε-amino group into the azide by diazo transfer allowing further functionalization by click chemistry. Mercapto groups can be introduced via acylation of c(RGDfK) with S-acetylthioacetic acid (SATA).

Formula: C₂₇H₄₁N₉O₇

Purity: 98.0%

Color and Shape: White

Molecular weight: 603.68

Ref: 01-4069635

Cyclo(RGDfK)

CAS: 161552-03-0

Formula: C₂₇H₄₁N₉O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 603.6705

Ref: IN-DA00AOJO

Cyclo(-RGDfK)

CAS: 161552-03-0

Cyclo(-RGDfK)

Purity: ≥95%

Molecular weight: 603.67g/mol

Ref: 54-BUP08387

Cyclo(-RGDfK)

CAS: 161552-03-0

Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.

Formula: C₂₇H₄₁N₉O₇

Purity: 95.29% - >99.99%

Color and Shape: Solid

Molecular weight: 603.67

Ref: TM-T6812

Cyclo(Arg-Gly-Asp-D-Phe-Lys)

CAS: 161552-03-0

Cyclo(Arg-Gly-Asp-D-Phe-Lys) is a small molecule drug that binds to the integrin receptor and blocks the growth of solid tumours. It has been shown to inhibit angiogenesis, especially in choroidal neovascularization in mice. Cyclo(Arg-Gly-Asp-D-Phe-Lys) is a cyclic peptide with biological properties that are similar to those of the natural amino acids found in protein. This drug has been shown to be safe for use in humans and animals, with no observed toxicity or side effects.

Formula: C₂₇H₄₁N₉O₇

Purity: Min. 95%

Molecular weight: 603.68 g/mol

Ref: 3D-PCI-3661-PI

Cyclo(Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate

CAS: 161552-03-0

Cyclo(Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate is a cyclic peptide, which functions as an integrin receptor antagonist. It is synthesized through solid-phase peptide synthesis, utilizing a sequence based on known integrin-binding motifs. The cyclic structure confers greater stability and binding affinity compared to linear counterparts.

Formula: C₂₇H₄₁N₉O₇•(C₂HF₃O₂)x

Purity: Min. 95%

Ref: 3D-BC183585

Cyclo (-RGDfK) Trifluoroacetic Acid Salt

Controlled Product

CAS: 161552-03-0

Applications Cyclo (-RGDfK) Trifluoroacetic Acid Salt is a potent inhibitor of αvβ3 integrin. Used in tumor therapy due to the targeting of the VEGFR2 gene by sRNA.
References Liu, L. et al.: Int. J. Nanomed., 9, 3509 (2014);

Formula: C₂₇H₄₁N₉O₇•x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 603.67 + x(114.02)

Ref: TR-C989895

Cyclo(Arg-Gly-Asp-D-Phe-Lys)

CAS: 161552-03-0

Cyclo(Arg-Gly-Asp-D-Phe-Lys) is a synthetic peptide that binds to the integrin receptor on pancreatic cancer cells. It has been shown to be an effective diagnostic tool for pancreatic cancer and other cancers, such as prostate, breast, and lung. Cyclo(Arg-Gly-Asp-D-Phe-Lys) selectively binds to cells with high levels of integrin receptors by using "a heterofunctional approach." This technique is used in the synthesis of peptides because it increases the stability of peptides. Cyclo(Arg-Gly-Asp-D-Phe-Lys) can be used for diagnosis or therapeutic purposes.

Formula: C₂₇H₄₁N₉O₇

Purity: Min. 95%

Molecular weight: 603.68 g/mol

Ref: 3D-PCI-3919-PI