SMARt751, identified by its CAS number 1616370-52-5, is a chemical compound that has garnered attention in various fields, particularly in medicinal chemistry and drug development. While specific characteristics such as its molecular structure, physical properties, and biological activity may vary, compounds like SMARt751 are typically evaluated for their efficacy, safety, and pharmacokinetic profiles. Generally, such substances may exhibit properties like solubility in organic solvents, stability under various conditions, and specific reactivity with biological targets. The compound may also be characterized by its mechanism of action, which could involve interactions with enzymes or receptors in biological systems. Additionally, SMARt751 may undergo rigorous testing for toxicity and therapeutic potential, making it a candidate for further research and development in pharmaceuticals. For precise details regarding its characteristics, including molecular weight, melting point, and specific applications, consulting specialized databases or scientific literature is recommended.

SMARt751

1616370-52-5: SMARt751, identified by its CAS number 1616370-52-5, is a chemical compound that has garnered attention in various fields, particularly in medicinal chemistry and drug development. While specific characteristics such as its molecular structure, physical properties, and biological activity may vary, compounds like SMARt751 are typically evaluated for their efficacy, safety, and pharmacokinetic profiles. Generally, such substances may exhibit properties like solubility in organic solvents, stability under various conditions, and specific reactivity with biological targets. The compound may also be characterized by its mechanism of action, which could involve interactions with enzymes or receptors in biological systems. Additionally, SMARt751 may undergo rigorous testing for toxicity and therapeutic potential, making it a candidate for further research and development in pharmaceuticals. For precise details regarding its characteristics, including molecular weight, melting point, and specific applications, consulting specialized databases or scientific literature is recommended.

4,4,4-Trifluoro-1-(4-(4-fluorophenyl)piperidin-1-yl)butan-1-one

SMARt751 targets the transcriptional regulator VirS, inhibiting its ability to bind DNA, which in turn enhances the expression of the mymA operon and activates Ethionamide. This activation increases the antimicrobial efficacy of Ethionamide against Mycobacterium tuberculosis, and overcomes its resistance. Furthermore, SMARt751 augments Ethionamide's antibacterial activity in mouse models and reduces its effective dose. Additionally, SMARt751 can permeate the blood-brain barrier.

CAS 1616370-52-5

SMARt751

4,4,4-Trifluoro-1-(4-(4-fluorophenyl)piperidin-1-yl)butan-1-one

Ref: 54-PC1006433

SMARt751

Ref: TM-T205582