CAS 1616393-25-9

4-Pyrimidinecarboxamide, 6-(3-azetidinylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-

Description:

4-Pyrimidinecarboxamide, 6-(3-azetidinylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]- is a complex organic compound characterized by its pyrimidine and isoquinoline moieties, which contribute to its biological activity. The presence of the azetidine ring suggests potential interactions with biological targets, possibly influencing its pharmacological properties. This compound features multiple functional groups, including an amide and a hydroxyl group, which can enhance solubility and reactivity. Its stereochemistry, indicated by the (2S) configuration, may play a crucial role in its interaction with biological systems, affecting its efficacy and safety profile. The molecular structure suggests potential applications in medicinal chemistry, particularly in the development of therapeutics targeting specific pathways. As with many compounds of this nature, understanding its stability, solubility, and reactivity under various conditions is essential for further research and application. Overall, this compound represents a significant interest in the field of drug discovery and development.

Formula: C₂₀H₂₆N₆O₂

Synonyms:

• 4-Pyrimidinecarboxamide, 6-(3-azetidinylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-

PRMT5 ligand 1

CAS: 1616393-25-9

PRMT5ligand 1 is a ligand of PRMT5, used as a target protein ligand in the synthesis of the PROTAC degrader MS4322.

Formula: C₂₀H₂₆N₆O₂

Color and Shape: Solid

Molecular weight: 382.459

Ref: TM-T205416