CAS: 1616493-44-7 - N-(2-Amino-4-fluorophenyl)-4-[[[(2E)-1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide

Formula: C₂₂H₁₉FN₄O₂

InChI: InChI=1S/C22H19FN4O2/c23-18-8-9-20(19(24)12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H,14,24H2,(H,26,28)(H,27,29)/b10-5+

InChI key: InChIKey=SZMJVTADHFNAIS-BJMVGYQFSA-N

SMILES: O=C(C=CC=1C=NC=CC1)NCC2=CC=C(C=C2)C(=O)NC3=CC=C(F)C=C3N

Synonyms:

• HBI 8000
• N-(2-Amino-4-fluorophenyl)-4-[[[(2E)-1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide
• Tucidinostat
• Epidaza
• Benzamide, N-(2-amino-4-fluorophenyl)-4-[[[(2E)-1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-

Tucidinostat

CAS: 1616493-44-7

• Formula: C₂₂H₁₉FN₄O₂
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 390.4103

Chidamide (Tucidinostat)

CAS: 1616493-44-7

• Formula: C₂₂H₁₉FN₄O₂
• Color and Shape: Off-White Solid
• Molecular weight: 390.42

Chidamide-d4 (Tucidinostat-d4)

CAS: 1616493-44-7

• Formula: C₂₂H₁₅D₄FN₄O₂
• Molecular weight: 394.44

Tucidinostat

CAS: 1616493-44-7

Tucidinostat is an oral HDAC1/2/3/10 inhibitor (IC50: 67-160 nM), weaker on HDAC8/11, inactive on HDAC4/5/6/7/9.

• Formula: C₂₂H₁₉FN₄O₂
• Purity: 97.01% - 98.76%
• Color and Shape: Solid
• Molecular weight: 390.41

Chidamide-13C6 (Tucidinostat-13C6)

CAS: 1616493-44-7

• Formula: C₆C₁₆H₁₉FN₄O₂
• Molecular weight: 396.37

Chidamide

CAS: 1616493-44-7

Applications Chidamide is a newly designed histone deacetylase inhibitor that induces an antitumor effect in …

• Formula: C₂₂H₁₉FN₄O₂
• Color and Shape: Neat
• Molecular weight: 390.41

Tucidinostat

CAS: 1616493-44-7

De-5-fluoro 4-Fluorochidamide is a potent inhibitor of histone deacetylases (HDACs) that was synthesized as a …

• Formula: C₂₂H₁₉FN₄O₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 390.41 g/mol