CAS 161709-56-4

1-Naphthylsulfonyl-L-isoleucyl-L-tryptophanal

Description:

1-Naphthylsulfonyl-L-isoleucyl-L-tryptophanal, identified by its CAS number 161709-56-4, is a chemical compound that features a complex structure combining a naphthyl sulfonyl group with amino acid residues, specifically L-isoleucine and L-tryptophan. This compound is characterized by its sulfonamide functional group, which typically enhances solubility and reactivity. The presence of the naphthyl moiety contributes to its aromatic properties, potentially influencing its interactions in biological systems. The amino acid components suggest that this compound may exhibit biological activity, possibly acting as a peptide or a precursor in biochemical pathways. Its structural complexity may also imply specific stereochemical configurations, which can affect its pharmacological properties. Overall, 1-Naphthylsulfonyl-L-isoleucyl-L-tryptophanal is of interest in medicinal chemistry and biochemistry, particularly in the context of drug design and development, due to its potential interactions with biological targets.

Formula: C₂₇H₂₉N₃O₄S

Synonyms:

• Tak-726

1-Naphthalenylsulfonyl-Ile-Trp-aldehyde

CAS: 161709-56-4

Cell-permeable and reversible inhibitor of cathepsin L, a lysosomal cysteine protease ( IC₅₀ 1.9 nM). 1-Naphthalenylsulfonyl-IW-CHO inhibited the release of Ca²⁺ and hydroxyproline from bone in an in vitro bone culture system. It should be useful for the treatment of osteoporosis.

Formula: C₂₇H₂₉N₃O₄S

Purity: 98.5%

Molecular weight: 491.61

Ref: 01-4029154

1-Naphthalenylsulfonyl-Ile-Trp-aldehyde

CAS: 161709-56-4

1-Naphthalenylsulfonyl-Ile-Trp-aldehyde is a recombinant protein that has protease activity. It is a serine protease that cleaves proteins at the amino acid sequence Ser-Xaa-Gly or Ser-Xaa. The recombinant protein has been shown to have proteolytic activity and can be used in assays to measure the amount of β-catenin, collagen, and growth factor in cells. 1-Naphthalenylsulfonyl-Ile-Trp-aldehyde also binds to monoclonal antibodies and can be used as a neutralizing agent for these proteins. This recombinant protein also has been shown to inhibit the growth of lung fibroblasts.

Formula: C₂₇H₂₉N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 491.6 g/mol

Ref: 3D-FN111089