CAS 161715-21-5

(1R,5S,6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid

Description:

The chemical substance known as (1R,5S,6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid, with CAS number 161715-21-5, is a synthetic antibiotic belonging to the carbapenem class. Carbapenems are characterized by their broad-spectrum antibacterial activity, making them effective against a wide range of Gram-positive and Gram-negative bacteria. This particular compound features a unique thiazolinyl substituent, which contributes to its pharmacological properties. The stereochemistry indicated by the (1R,5S,6S) configuration suggests specific spatial arrangements of its atoms, which can influence its biological activity and interaction with bacterial enzymes. The presence of a carboxylic acid functional group enhances its solubility and stability in biological systems. Overall, this compound is of interest in medicinal chemistry for its potential use in treating infections caused by resistant bacterial strains, although its specific clinical applications and efficacy would require further investigation and validation through research studies.

Formula: C₁₆H₂₁N₃O₄S₂

InChI: InChI=1S/C16H21N3O4S2/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)25-9-5-18(6-9)16-17-3-4-24-16/h7-11,20H,3-6H2,1-2H3,(H,22,23)/t7-,8-,10-,11-/m1/s1

InChI key: InChIKey=GXXLUDOKHXEFBQ-YJFSRANCSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1SC3CN(C3)C4=NCCS4)[H]

Synonyms:

• (4R,5S,6S)-3-[[1-(4,5-Dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[4α,5β,6β(R*)]]-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-
• L-036
• Ljc-11036
• Spr 859
• Tebipenem
• Tebipenem Impurity 5
• Tibipenem intermediate 2
• Tebipenem USP/EP/BP
• (4R,5S,6S)-3-[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicaci
• LJC11036

1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid,3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[4a,5b,6b(R*)]]-

CAS: 161715-21-5

Formula: C₁₆H₂₁N₃O₄S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 383.4856

Ref: IN-DA01EB13

Tebipenem

CAS: 161715-21-5

Tebipenem

Purity: ≥98%

Molecular weight: 383.49g/mol

Ref: 54-BUP16734

Tebipenem

CAS: 161715-21-5

Tebipenem

Purity: 98%

Molecular weight: 383.49g/mol

Ref: 54-OR1026169

Tebipenem-d4

CAS: 161715-21-5

Formula: C₁₆H₁₇D₄N₃O₄S₂

Color and Shape: Yellow Solid

Molecular weight: 387.51

Ref: 4Z-T-9927

Tebipenem

CAS: 161715-21-5

Formula: C₁₆H₂₁N₃O₄S₂

Color and Shape: Off-White Solid

Molecular weight: 383.48

Ref: 4Z-T-995

Tebipenem

CAS: 161715-21-5

Tebipenem is a carbapenem antibiotic with action on bacterial cell wall synthesis and is used for treating multidrug-resistant bacterial infections, including complicated urinary tract infections.

Formula: C₁₆H₂₁N₃O₄S₂

Purity: Min. 95%

Molecular weight: 383.49 g/mol

Ref: 3D-LGA71521

Tebipenem

CAS: 161715-21-5

Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.

Formula: C₁₆H₂₁N₃O₄S₂

Purity: 98% - 99.77%

Color and Shape: Solid

Molecular weight: 383.49

Ref: TM-T17021