CAS 161715-21-5: (1R,5S,6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid

Description: The chemical substance known as (1R,5S,6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid, with CAS number 161715-21-5, is a synthetic antibiotic belonging to the carbapenem class. Carbapenems are characterized by their broad-spectrum antibacterial activity, making them effective against a wide range of Gram-positive and Gram-negative bacteria. This particular compound features a unique thiazolinyl substituent, which contributes to its pharmacological properties. The stereochemistry indicated by the (1R,5S,6S) configuration suggests specific spatial arrangements of its atoms, which can influence its biological activity and interaction with bacterial enzymes. The presence of a carboxylic acid functional group enhances its solubility and stability in biological systems. Overall, this compound is of interest in medicinal chemistry for its potential use in treating infections caused by resistant bacterial strains, although its specific clinical applications and efficacy would require further investigation and validation through research studies.

Formula: C₁₆H₂₁N₃O₄S₂

InChI: InChI=1S/C16H21N3O4S2/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)25-9-5-18(6-9)16-17-3-4-24-16/h7-11,20H,3-6H2,1-2H3,(H,22,23)/t7-,8-,10-,11-/m1/s1

InChI key: InChIKey=GXXLUDOKHXEFBQ-YJFSRANCSA-N

SMILES: O=C(O)C1=C(SC2CN(C3=NCCS3)C2)C(C)C4N1C(=O)C4C(O)C

Synonyms:

• (4R,5S,6S)-3-[[1-(4,5-Dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[4α,5β,6β(R*)]]-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-
• L-036
• Ljc-11036
• Spr 859
• Tebipenem

1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid,3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[4a,5b,6b(R*)]]-

CAS: 161715-21-5

• Formula: C₁₆H₂₁N₃O₄S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 383.4856

Tebipenem

CAS: 161715-21-5

• Formula: C₁₆H₂₁N₃O₄S₂
• Color and Shape: Off-White Solid
• Molecular weight: 383.48

Tebipenem-d4

CAS: 161715-21-5

• Formula: C₁₆H₁₇D₄N₃O₄S₂
• Color and Shape: Yellow Solid
• Molecular weight: 387.51

Tebipenem

CAS: 161715-21-5

Tebipenem is a natural compound that belongs to the class of beta-lactam antibiotics. It has …

• Formula: C₁₆H₂₁N₃O₄S₂
• Purity: Min. 95%
• Molecular weight: 383.49 g/mol

Tebipenem

CAS: 161715-21-5

Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative …

• Formula: C₁₆H₂₁N₃O₄S₂
• Purity: 98% - 99.77%
• Color and Shape: Solid
• Molecular weight: 383.49