CAS 161735-79-1

Rasagiline mesylate

Description:

Rasagiline mesylate is a selective, irreversible monoamine oxidase B (MAO-B) inhibitor primarily used in the treatment of Parkinson's disease. It is characterized by its ability to increase dopamine levels in the brain, thereby alleviating symptoms associated with this neurodegenerative disorder. The substance appears as a white to off-white crystalline powder and is soluble in water and organic solvents, which facilitates its formulation in various pharmaceutical preparations. Rasagiline mesylate has a molecular formula that reflects its complex structure, incorporating both a rasagiline base and a mesylate group, which enhances its stability and bioavailability. The compound is typically administered orally and is known for its favorable pharmacokinetic profile, including a long half-life that allows for once-daily dosing. Additionally, it has a low potential for drug-drug interactions, making it a preferred choice in combination therapies for Parkinson's disease. As with any medication, it is essential to monitor for potential side effects and contraindications during treatment.

Formula: C₁₃H₁₇NO₃S

InChI: InChI=1/C12H13N.CH4O3S/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12;1-5(2,3)4/h1,3-6,12-13H,7-9H2;1H3,(H,2,3,4)/t12-;/m1./s1

SMILES: C#CCN[C@@H]1CCc2ccccc12.CS(=O)(=O)O

Synonyms:

• (1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine methanesulfonate (1:1)
• (1R)-N-(Prop-2-yn-1-yl)indan-1-amine methanesulfonate (1:1)
• 1H-inden-1-amine, 2,3-dihydro-N-2-propyn-1-yl-, (1R)-, methanesulfonate (1:1)
• 1H-inden-1-amine, 2,3-dihydro-N-2-propynyl-, (1R)-, methanesulfonate (1:1)
• acide méthanesulfonique - (1R)-N-prop-2-yn-1-yl-2,3-dihydro-1H-indén-1-amine (1:1)
• Methansulfons?ure--(1R)-N-prop-2-in-1-yl-2,3-dihydro-1H-inden-1-amin(1:1)
• (1R)-N-prop-2-yn-1-yl-2,3-dihydro-1H-inden-1-amine methanesulfonate

Rasagiline Mesylate

CAS: 161735-79-1

Formula: C₁₂H₁₃N·CH₄O₃S

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 267.34

Ref: 3B-R0213

1H-Inden-1-amine, 2,3-dihydro-N-2-propyn-1-yl-, (1R)-, methanesulfonate (1:1)

CAS: 161735-79-1

Formula: C₁₃H₁₇NO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 267.3440

Ref: IN-DA001VUM

Rasagiline mesylate

CAS: 161735-79-1

Rasagiline mesylate

Purity: 98%

Molecular weight: 267.34g/mol

Ref: 54-OR1029164

Rasagiline Mesylate

CAS: 161735-79-1

Rasagiline Mesylate

Purity: ≥98%

Molecular weight: 267.34g/mol

Ref: 54-BUP13823

Rasagiline Mesylate

CAS: 161735-79-1

Formula: C₁₂H₁₃N·CH₄O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 171.24 96.10

Ref: 4Z-R-195

Rasagiline mesylate

CAS: 161735-79-1

Formula: C₁₂H₁₃N·CH₄O₃S

Molecular weight: 267.34

Ref: 7W-GP2635

Rasagiline Mesilate

Controlled Product

CAS: 161735-79-1

Formula: C₁₂H₁₃N·CH₄O₃S

Color and Shape: Neat

Molecular weight: 267.34

Ref: 86-MM3667.00

Rasagiline Mesylate

CAS: 161735-79-1

Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.

Formula: C₁₃H₁₇NO₃S

Purity: 99.33%

Color and Shape: White Powder

Molecular weight: 267.34

Ref: TM-T6962

Rasagiline Mesylate

CAS: 161735-79-1

Applications Rasagiline is a selective irreversible MAO-B inhibitor (1,2,3,4). Rasagiline is an Antiparkinsonian agent.
References (1) Rabey, J.M., et al.: Clin. Neuropharmacol., 23, 324 (2000) (2) Glezer, S., et al.: Eur. J. Pharmacol., 472, 173 (2003) (3) Youdim, M.B.H., et al.: Biochem. Pharmacol., 66, 1635 (2003) (4) Chen, J.J., et al.: J. Clin. Pharmacol., 45, 878 (2005)

Formula: C₁₂H₁₃N·CH₄O₃S

Color and Shape: White

Molecular weight: 267.34

Ref: TR-R126000

Rasagiline Mesylate

CAS: 161735-79-1

Formula: C₁₂H₁₃NCH₄O₃S

Molecular weight: 171.24 : 96.10

Ref: ST-EA-CP-R10011

Rasagiline mesylate

Controlled Product

CAS: 161735-79-1

Monoamine oxidase-B inhibitor; anti-parkinsonian; neuroprotective

Formula: C₁₂H₁₃N•CH₄O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 267.35 g/mol

Ref: 3D-FR15445