CAS 161743-35-7
:3'-Demethylstaurosporine
Description:
3'-Demethylstaurosporine is a synthetic compound that belongs to the class of staurosporine derivatives, which are known for their potent inhibitory effects on various protein kinases. This compound is characterized by its complex tetracyclic structure, which is typical of staurosporine analogs, and it exhibits a range of biological activities, including anti-cancer properties. The absence of a methyl group at the 3' position distinguishes it from staurosporine, potentially altering its pharmacological profile and selectivity for specific kinases. 3'-Demethylstaurosporine has been studied for its ability to induce apoptosis in cancer cells and may also influence cell cycle regulation. Its mechanism of action typically involves the inhibition of signaling pathways that are crucial for cell proliferation and survival. As with many kinase inhibitors, the compound's efficacy and safety profile are subjects of ongoing research, particularly in the context of targeted cancer therapies. Additionally, due to its structural complexity, it may exhibit unique solubility and stability characteristics that are relevant for formulation and delivery in therapeutic applications.
Formula:C27H24N4O3
Synonyms:- (9S,10R,11R,13R)-11-(methylamino)-2,3,10,11,12,13-hexahydro-10-hydroxy-9-methyl-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
- 3-Demethoxy-3-hydroxystaurosporine
- 3'-Demethylstaurosporine
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