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CAS 161796-84-5

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Esomeprazole potassium

Description:
Esomeprazole potassium is a proton pump inhibitor (PPI) primarily used to treat gastroesophageal reflux disease (GERD) and other conditions associated with excessive stomach acid production. It is the S-enantiomer of omeprazole, which means it has a specific three-dimensional arrangement that enhances its efficacy. This compound works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a significant reduction in gastric acid secretion. Esomeprazole potassium is typically administered in the form of enteric-coated tablets or capsules to protect it from degradation in the acidic environment of the stomach. It is characterized by its high solubility in alkaline conditions, which facilitates its absorption in the intestines. Common side effects may include headache, nausea, and abdominal pain, while long-term use has been associated with potential risks such as vitamin B12 deficiency and increased susceptibility to gastrointestinal infections. Overall, esomeprazole potassium is a well-established medication with a favorable safety profile when used as directed.
Formula:C17H19KN3O3S
InChI:InChI=1S/C17H19N3O3S.K/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3,(H,19,20);/t24-;/m0./s1
InChI key:InChIKey=VGDAWUJEXXBODZ-JIDHJSLPSA-N
SMILES:S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3.[K]
Synonyms:
  • (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole potassium salt
  • (S)-Omeprazole potassium
  • 1H-Benzimidazole, 5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, potassium salt
  • 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, potassium salt, (S)-
  • 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, potassium salt (1:1)
  • 6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole potassium salt (1:1)
  • Esomeprazole potassium salt
  • Esomeprazole potassium
  • (S)-5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]
  • (R)-5-METHOXY-2-((4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYLSULFINYL)BENZO[D]IMIDAZOL-1-IDE POTASSIUM SALT
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