CAS 161814-49-9
:AMPRENAVIR
Description:
Amprenavir is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of drugs known as protease inhibitors, which work by inhibiting the protease enzyme, crucial for the viral replication process. The molecular formula of amprenavir is C20H27N3O5S, and it features a sulfonamide group, contributing to its pharmacological activity. Amprenavir is typically administered orally and is known for its relatively low pill burden compared to other antiretrovirals. It exhibits a moderate bioavailability and is metabolized primarily by the liver, with cytochrome P450 enzymes playing a significant role in its clearance. Common side effects may include gastrointestinal disturbances, rash, and potential lipid abnormalities. Due to the development of resistance, amprenavir is often used in combination with other antiretroviral agents to enhance efficacy and reduce the likelihood of viral resistance. Its stability and solubility characteristics make it suitable for formulation in various dosage forms, including capsules and oral solutions.
Formula:C25H35N3O6S
InChI:InChI=1/C25H35N3O6S/c1-18(2)15-28(35(31,32)22-10-8-20(26)9-11-22)16-24(29)23(14-19-6-4-3-5-7-19)27-25(30)34-21-12-13-33-17-21/h3-11,18,21,23-24,29H,12-17,26H2,1-2H3,(H,27,30)/t21?,23-,24+/m0/s1
InChI key:InChIKey=YMARZQAQMVYCKC-OEMFJLHTSA-N
SMILES:N(S(=O)(=O)C1=CC=C(N)C=C1)(C[C@H]([C@H](CC2=CC=CC=C2)NC(O[C@H]3CCOC3)=O)O)CC(C)C
Synonyms:- 141W94
- 141W94, KVX-478, Agenerase, Prozei,
- Agenerase
- Amprenavir & its intermediates(R&D)
- Angenerase
- Carbamic acid, (1S,2R)-3-(4-aminophenyl)sulfonyl(2-methylpropyl)amino-2-hydroxy-1-(phenylmethyl)propyl-, (3S)-tetrahydro-3-furanyl ester
- Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester
- Carbamic acid, [3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, tetrahydro-3-furanyl ester, [3S-[3R*(1R*,2S*)]]-
- Kvx-478
- Prozei
- Samprenavir
- Vx 478
- tetrahydrofuran-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate
- Amprenavir(KVX-478)
- AMPRENAVIR
- AMprenavir(agenerase)
- [(3S)-Oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
- See more synonyms
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Found 10 products.
(3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)(4-aminobenzene)sulfonamido]-1-phenylbutan-2-yl]carbamate
CAS:Formula:C25H35N3O6SPurity:97%Color and Shape:SolidMolecular weight:505.6269Amprenavir
CAS:Formula:C25H35N3O6SPurity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:505.63(S)-Tetrahydrofuran-3-Yl ((2S,3R)-4-((4-Amino-N-Isobutylphenyl)Sulfonamido)-3-Hydroxy-1-Phenylbutan-2-Yl)Carbamate
CAS:(S)-Tetrahydrofuran-3-Yl ((2S,3R)-4-((4-Amino-N-Isobutylphenyl)Sulfonamido)-3-Hydroxy-1-Phenylbutan-2-Yl)CarbamatePurity:98%Molecular weight:505.63g/molAmprenavir
CAS:<p>Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV)</p>Formula:C25H35N3O6SPurity:99.60% - 99.87%Color and Shape:Off-White To Pale YellowMolecular weight:505.63Amprenavir
CAS:Controlled Product<p>Applications A selective HIV protease inhibitor. An analogue of Ritonavir.<br>References Adkins, J.C., et al.: Drugs, 55, 837 (1998)<br></p>Formula:C25H35N3O6SColor and Shape:White To BeigeMolecular weight:505.63Amprenavir
CAS:<p>Anti-retroviral; HIV protease inhibitor</p>Formula:C25H35N3O6SPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:505.63 g/mol
![(3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)(4-aminobenzene)sulfonamido]-1-phenylbu…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001VWI.jpg&w=3840&q=75)
