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CAS 161848-60-8

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5-bromouridine 5'-triphosphate sodium

Description:
5-Bromouridine 5'-triphosphate sodium (5-BrUTP) is a nucleotide analog that serves as a substrate for RNA polymerases in various biochemical applications. It is characterized by the presence of a bromine atom at the 5-position of the uridine base, which can influence its reactivity and incorporation into RNA. The triphosphate group is essential for its role in RNA synthesis, as it provides the necessary energy for the polymerization process. This compound is typically used in research settings, particularly in studies involving RNA synthesis, transcriptional regulation, and the development of RNA-based therapeutics. Its sodium salt form enhances solubility in aqueous solutions, making it suitable for in vitro experiments. Additionally, 5-BrUTP can be utilized in labeling experiments due to the bromine atom, which can be detected using various analytical techniques. Overall, 5-bromouridine 5'-triphosphate sodium is a valuable tool in molecular biology and biochemistry for studying RNA dynamics and function.
Formula:Na3
InChI:InChI=1/3Na/q3*+1
SMILES:[Na].[Na].[Na]
Synonyms:
  • Uridine 5-(tetrahydrogen triphosphate), 5-bromo-, sodium salt
  • Sodium(+1) Cation
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