CAS 1618672-71-1

1,5-Bis[(E)-2-(3,4-dichlorophenyl)vinyl]-2,4-dinitrobenzene

Description:

1,5-Bis[(E)-2-(3,4-dichlorophenyl)vinyl]-2,4-dinitrobenzene is a synthetic organic compound characterized by its complex structure, which includes multiple aromatic rings and functional groups. This compound features two (E)-vinyl groups attached to a central dinitrobenzene moiety, contributing to its potential as a versatile building block in organic synthesis. The presence of dichlorophenyl groups enhances its electronic properties, making it of interest in various applications, including materials science and pharmaceuticals. The dinitro groups are known for their electron-withdrawing effects, which can influence the compound's reactivity and stability. Additionally, the compound may exhibit interesting optical properties due to its conjugated system, potentially making it useful in dye applications or as a precursor for further chemical modifications. Safety and handling considerations are important, as compounds with nitro groups can be sensitive and may pose environmental hazards. Overall, this compound exemplifies the intricate interplay of structure and function in organic chemistry.

Formula: C₂₂H₁₂Cl₄N₂O₄

Synonyms:

• NSC 636819
• Benzene, 1,5-bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitro-
• 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene
• 1,5-Bis[(E)-2-(3,4-dichlorophenyl)vinyl]-2,4-dinitrobenzene

NSC 636819

CAS: 1618672-71-1

NSC 636819 is a histone deacetylase (HDAC) inhibitor that is used in cancer research. This drug has been shown to inhibit homologous recombination and growth factor-induced DNA repair by blocking the binding of HDAC1 to the substrate, thereby preventing histone deacetylation and reversing the effects of tumor suppressor genes. NSC 636819 also inhibits 2-hydroxyglutarate production, which leads to a higher rate of homologous recombination, leading to cell death. The administration of this drug has been shown to increase tumor size in mouse models with an IDH2 mutation. In addition, NSC 636819 has been shown to be effective in inhibiting cell proliferation in enteroendocrine cells and immunostaining for tgf-β.

Formula: C₂₂H₁₂Cl₄N₂O₄

Purity: Min. 95%

Molecular weight: 510.1 g/mol

Ref: 3D-TPC67271

NSC-636819

CAS: 1618672-71-1

NSC-636819 is a novel inhibitor of KDM4A/KDM4B.

Formula: C₂₂H₁₂Cl₄N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 510.15

Ref: TM-T28208