CAS 161877-70-9

dabcyl-tyr-val-ala-asp-ala-pro-val-*edans

Description:

Dabcyl-tyr-val-ala-asp-ala-pro-val-edans is a synthetic peptide that serves as a fluorescent probe, commonly used in biochemical and biophysical research. This compound features a dabcyl moiety, which acts as a quencher, and an edans group, which serves as a fluorophore. The peptide sequence includes various amino acids, contributing to its structural and functional properties. The presence of specific amino acids like tyrosine, valine, alanine, and aspartic acid influences its interactions with other biomolecules, making it useful in studies involving enzyme activity, protein-protein interactions, and cellular processes. The unique combination of the dabcyl and edans groups allows for fluorescence resonance energy transfer (FRET) applications, where energy transfer occurs between the donor (edans) and the acceptor (dabcyl) upon excitation. This characteristic is particularly valuable in monitoring conformational changes in proteins or the dynamics of molecular interactions in real-time. Overall, this compound is a versatile tool in the field of molecular biology and biochemistry for studying various biological phenomena.

Formula: C₆₁H₇₆N₁₂O₁₄S

InChI: InChI=1/C61H76N12O14S/c1-34(2)52(63-30-29-62-46-14-9-13-45-44(46)12-10-16-50(45)88(85,86)87)59(82)69-58(81)49-15-11-31-73(49)61(84)37(6)65-56(79)48(33-51(75)76)66-54(77)36(5)64-60(83)53(35(3)4)68-57(80)47(32-38-17-27-43(74)28-18-38)67-55(78)39-19-21-40(22-20-39)70-71-41-23-25-42(26-24-41)72(7)8/h9-10,12-14,16-28,34-37,47-49,52-53,62-63,74H,11,15,29-33H2,1-8H3,(H,64,83)(H,65,79)(H,66,77)(H,67,78)(H,68,80)(H,75,76)(H,69,81,82)(H,85,86,87)/b71-70+/t36-,37-,47-,48-,49-,52-,53-/m0/s1

Synonyms:

• N-[(4-{(E)-[4-(dimethylamino)phenyl]diazenyl}phenyl)carbonyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-N-[(2S)-3-methyl-2-({2-[(5-sulfonaphthalen-1-yl)amino]ethyl}amino)butanoyl]-L-prolinamide

L-Valinamide, N-[4-[[4-(dimethylamino)phenyl]azo]benzoyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]- (9CI)

CAS: 161877-70-9

Formula: C₆₁H₇₆N₁₂O₁₄S

Molecular weight: 1233.3931

Ref: IN-DA001VYB

DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt

CAS: 161877-70-9

DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt is a reactive dye that has been shown to bind to the granule neurons of the cerebellum in HL60 cells. It is used as an indicator of protease activity, as it undergoes hydrolysis by serine proteases. DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt has also been shown to activate caspase 1 and cause neuronal death in a number of experimental models. This molecule is used for fluorescent labeling and detection of protein synthesis, as well as for visualization of the termini of proteins and other molecules. DABCYL Tyr Val Ala Asp Ala Pro Val EDANS trifluoroacetate salt is also known to be an antiinflammatory agent that may be effective against infectious diseases such as HIV,

Formula: C₆₁H₇₆N₁₂O₁₄S

Purity: Min. 95%

Molecular weight: 1,233.39 g/mol

Ref: 3D-FD110900