CAS 161973-10-0

Esomeprazole magnesium

Description:

Esomeprazole magnesium is a proton pump inhibitor (PPI) primarily used to treat gastroesophageal reflux disease (GERD) and other conditions associated with excessive stomach acid production. It is the magnesium salt of esomeprazole, which is the S-enantiomer of omeprazole. This compound works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a decrease in gastric acid secretion. Esomeprazole magnesium is typically administered in oral form and is known for its improved bioavailability compared to its racemic counterpart. The substance is characterized by its white to off-white crystalline powder appearance, and it is soluble in water and methanol, making it suitable for various pharmaceutical formulations. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations occurring within a few hours after administration. Common side effects may include headache, nausea, and abdominal pain, while long-term use has been associated with potential risks such as vitamin B12 deficiency and increased susceptibility to gastrointestinal infections.

Formula: (C₁₇H₁₈N₃O₃S)₂·Mg

InChI: InChI=1/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2/t2*24-;/m00./s1

InChI key: InChIKey=KWORUUGOSLYAGD-UHFFFAOYSA-N

SMILES: C(S1=O[Mg+2]2([N]3=C(S(CC4=C(C)C(OC)=C(C)C=N4)=O2)[N-]C=5C3=CC=C(OC)C5)[N]6=C1[N-]C=7C6=CC=C(OC)C7)C8=C(C)C(OC)=C(C)C=N8

Synonyms:

• (-)-Omeprazole magnesium
• (S)-Omeprazole magnesium
• (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN³]magnesium
• H 199/18
• Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
• Magnesium Bis(5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide)
• Magnesium, bis[5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]-, [T-4-(S),(S)]-
• Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN³]-, (T-4)-
• Nexium
• Perprazole
• Raciper
• magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide)
• Esomeprazole magnesium
• (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]magnesium
• Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, (T-4)-
• Esomeprazole magnesium Q: What is the CAS Number of
• Esomeprazole Magnesium(Random Configuration)
• Esomeprazole magnesium Esomeprazole magnesium(API)
• 5-Methoxy-2-((S)-((4-Methoxy-3,5-diMethyl-2-pyridyl)Methyl)sulfinyl-1H-benziMidazole MagnesiuM salt
• ESOMEPRAZOLE MAGNESIUM/SODIUM
• Esomeprazole magnesiumQ: What is
• (S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, magnesium salt (2:1)
• Esomeprazole magnesium Q: What is the storage condition of
• Magnesium Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]benzimidazol-1-ide]
• Esomeprazole magnesium Q: What are the applications of
• Esomeprazole magnesium USP/EP/BP
• Chebi:50309
• Esomeprazole magnesium (S-Omeprazole magnesium)
• NEXIUM(esomeprazolemagnesium)
• Bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) magnesium
• Esomeprazole magnesium API
• Esomeprazole magnesium 5-Methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinylmethyl)sulfinyl]-1H-benzimidazole magnesium salt
• ESOMEPRAZOLE MAGNESIUM SAMPLE
• EsMeprazole Magne-siuM Trihydrate
• S-Form magnesium salt

Esomeprazole Magnesium(Random Configuration)

CAS: 161973-10-0

Formula: C₃₄H₃₆MgN₆O₆S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 713.1212

Ref: IN-DA001SKP

Esomeprazole Magnesium Salt

CAS: 161973-10-0

Formula: C₁₇H₁₈N₃O₃S·Mg

Color and Shape: White To Off-White Solid

Molecular weight: 2*344.41 24.30

Ref: 4Z-O-0213

Esomeprazole Magnesium

CAS: 161973-10-0

Esomeprazole Magnesium

Purity: ≥98%

Molecular weight: 713.12g/mol

Ref: 54-BUP13843

Esomeprazole Magnesium(Random Configuration)

CAS: 161973-10-0

Esomeprazole Magnesium(Random Configuration)

Purity: 99%

Molecular weight: 713.12g/mol

Ref: 54-IN11944

Esomeprazole Magnesium

CAS: 161973-10-0

Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.

Formula: C₃₄H₃₆MgN₆O₆S₂

Purity: 98.76% - 99.73%

Color and Shape: Solid

Molecular weight: 713.12

Ref: TM-T2686

Esomeprazole magnesium

CAS: 161973-10-0

Esomeprazole magnesium is a proton-pump inhibitor that is used to treat gastroesophageal reflux disease, Zollinger–Ellison syndrome, and other conditions. Esomeprazole magnesium binds to the H+/K+ ATPase enzyme in the stomach and inhibits acid production. It also decreases the release of histamine from cells in the stomach lining, thereby decreasing gastric acid secretion. This drug has been shown to be effective for treating Helicobacter pylori infections and reducing the risk of ulcers associated with nonsteroidal anti-inflammatory drugs in patients with hepatic impairment or those taking omeprazole. The efficacy of esomeprazole magnesium can be measured by its concentration-time curve, which can be determined through blood sampling.

Formula: (C₁₇H₁₈N₃O₃S)₂•Mg

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 713.12 g/mol

Ref: 3D-FE46488

Esomeprazole Magnesium

CAS: 161973-10-0

Formula: C₃₄H₃₆MgN₆O₆S₂

Molecular weight: 713.12

Ref: ST-EA-CP-E14022