CAS 161973-10-0: Esomeprazole magnesium
Description:Esomeprazole magnesium is a proton pump inhibitor (PPI) primarily used to treat gastroesophageal reflux disease (GERD) and other conditions associated with excessive stomach acid production. It is the magnesium salt of esomeprazole, which is the S-enantiomer of omeprazole. This compound works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a decrease in gastric acid secretion. Esomeprazole magnesium is typically administered in oral form and is known for its improved bioavailability compared to its racemic counterpart. The substance is characterized by its white to off-white crystalline powder appearance, and it is soluble in water and methanol, making it suitable for various pharmaceutical formulations. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations occurring within a few hours after administration. Common side effects may include headache, nausea, and abdominal pain, while long-term use has been associated with potential risks such as vitamin B12 deficiency and increased susceptibility to gastrointestinal infections.
Formula:C34H36MgN6O6S2
InChI:InChI=1S/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2
InChI key:InChIKey=KWORUUGOSLYAGD-UHFFFAOYSA-N
SMILES:N=1C=C(C(OC)=C(C1CS2=O[Mg+2]3(O=S(C=4[N-]C=5C=C(OC)C=CC5[N]43)CC6=NC=C(C(OC)=C6C)C)[N]7=C2[N-]C=8C=C(OC)C=CC87)C)C
- Synonyms:
- (-)-Omeprazole magnesium
- (S)-Omeprazole magnesium
- (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN<sup>3</sup>]magnesium
- H 199/18
- Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
- Magnesium Bis(5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide)
- Magnesium, bis[5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]-, [T-4-(S),(S)]-
- Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN<sup>3</sup>]-, (T-4)-
- Nexium
- Perprazole
- See more synonyms
- Raciper
- magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide)

Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, (T-4)-
Ref: IN-DA001SKP
1g | 58.00 € | ||
5g | 143.00 € | ||
100mg | 27.00 € | ||
250mg | 37.00 € |

Esomeprazole Magnesium Salt
Ref: 4Z-O-0213
5mg | 224.00 € | ||
10mg | 373.00 € | ||
25mg | 474.00 € | ||
50mg | 677.00 € | ||
100mg | 971.00 € |

Ref: 54-BUP13843
1g | 291.00 € | ||
25mg | 59.00 € | ||
50mg | 77.00 € | ||
100mg | 101.00 € | ||
200mg | 147.00 € |

Ref: 54-IN11944
1g | 49.00 € | ||
5g | 133.00 € | ||
25g | 405.00 € | ||
100g | 881.00 € | ||
250mg | 32.00 € |

Esomeprazole Magnesium
Ref: TM-T2686
25mg | 42.00 € | ||
50mg | 49.00 € | ||
100mg | 67.00 € | ||
200mg | 88.00 € | ||
1mL*10mM (DMSO) | 51.00 € |

Esomeprazole magnesium
Ref: 3D-FE46488
10g | 147.00 € | ||
25g | 175.00 € | ||
50g | 225.00 € | ||
100g | 299.00 € | ||
250g | 472.00 € |

Esomeprazole Magnesium
Ref: 3B-E1443
250mg | Discontinued | Request information |