CAS 162012-69-3: 7-Fluoro-6-Nitro-4(H)-Quinazoline

Description: 7-Fluoro-6-Nitro-4(H)-Quinazoline, with the CAS number 162012-69-3, is a synthetic organic compound belonging to the quinazoline class of heterocyclic compounds. This substance is characterized by the presence of a fluorine atom at the 7-position and a nitro group at the 6-position of the quinazoline ring, which contributes to its chemical reactivity and potential biological activity. Quinazolines are known for their diverse pharmacological properties, including antimicrobial, anti-inflammatory, and anticancer activities. The presence of the fluorine atom can enhance lipophilicity and metabolic stability, potentially influencing the compound's bioavailability and interaction with biological targets. The nitro group may also play a role in the compound's reactivity and ability to participate in various chemical reactions. Overall, 7-Fluoro-6-Nitro-4(H)-Quinazoline is of interest in medicinal chemistry and drug development, although specific applications and biological activities would require further investigation.

Formula: C₈H₄FN₃O₃

InChI: InChI=1/C8H4FN3O3/c9-5-2-6-4(1-7(5)12(14)15)8(13)11-3-10-6/h1-3H,(H,10,11,13)

Synonyms:

• 7-Fluoro-6-nitro-4-hydroxy-quinazoline
• 7-Fluoro-6-nitro-4-hydroxyquinazoline
• 7-fluoro-6-nitroquinazolin-4(1H)-one
• 7-Fluoro-6-Nitroquinazolin-4-Ol
• 7-Fluoro-6-Nitro-3,4-Dihydroquinazolin-4-One

7-Fluoro-6-nitroquinazolin-4(1H)-one

CAS: 162012-69-3

• Formula: C₈H₄FN₃O₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: Light yellow to Yellow to Orange powder to crystal
• Molecular weight: 209.14

4(3H)-Quinazolinone, 7-fluoro-6-nitro-

CAS: 162012-69-3

• Formula: C₈H₄FN₃O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 209.1341

Afatinib Impurity 48

CAS: 162012-69-3

• Formula: C₈H₄FN₃O₃
• Molecular weight: 209.14

7-Fluoro-6-nitro-1H-quinazolin-4-one

CAS: 162012-69-3

• Purity: 98+%
• Color and Shape: Solid
• Molecular weight: 209.13g/mol

7-Fluoro-6-nitro-4-hydroxyquinazoline

CAS: 162012-69-3

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 209.023669208

7-Fluoro-6-nitroquinazolin-4(3H)-one

CAS: 162012-69-3

Applications 7-Fluoro-6-nitroquinazolin-4(3H)-one, is an intermediate in the preparation of kinase inhibitors, such as ATP Site …

• Formula: C₈H₄FN₃O₃
• Color and Shape: Neat
• Molecular weight: 209.13

7-Fluoro-6-nitro-4-hydroxyquinazoline

CAS: 162012-69-3

Intermediate in the synthesis of afatinib

• Formula: C₈H₄FN₃O₃
• Purity: Min. 95%
• Molecular weight: 209.13 g/mol