CAS 162012-69-3

7-Fluoro-6-Nitro-4(H)-Quinazoline

Description:

7-Fluoro-6-Nitro-4(H)-Quinazoline, with the CAS number 162012-69-3, is a synthetic organic compound belonging to the quinazoline class of heterocyclic compounds. This substance is characterized by the presence of a fluorine atom at the 7-position and a nitro group at the 6-position of the quinazoline ring, which contributes to its chemical reactivity and potential biological activity. Quinazolines are known for their diverse pharmacological properties, including antimicrobial, anti-inflammatory, and anticancer activities. The presence of the fluorine atom can enhance lipophilicity and metabolic stability, potentially influencing the compound's bioavailability and interaction with biological targets. The nitro group may also play a role in the compound's reactivity and ability to participate in various chemical reactions. Overall, 7-Fluoro-6-Nitro-4(H)-Quinazoline is of interest in medicinal chemistry and drug development, although specific applications and biological activities would require further investigation.

Formula: C₈H₄FN₃O₃

InChI: InChI=1/C8H4FN3O3/c9-5-2-6-4(1-7(5)12(14)15)8(13)11-3-10-6/h1-3H,(H,10,11,13)

SMILES: c1c2c(cc(c1N(=O)=O)F)ncnc2O

Synonyms:

• 7-Fluoro-6-nitro-4-hydroxy-quinazoline
• 7-Fluoro-6-nitro-4-hydroxyquinazoline
• 7-fluoro-6-nitroquinazolin-4(1H)-one
• 7-Fluoro-6-Nitroquinazolin-4-Ol
• 7-Fluoro-6-Nitro-3,4-Dihydroquinazolin-4-One

7-Fluoro-6-nitroquinazolin-4(1H)-one

CAS: 162012-69-3

Formula: C₈H₄FN₃O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 209.14

Ref: 3B-F1091

4(3H)-Quinazolinone, 7-fluoro-6-nitro-

CAS: 162012-69-3

Formula: C₈H₄FN₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 209.1341

Ref: IN-DA001SMN

Afatinib Impurity 48

CAS: 162012-69-3

Formula: C₈H₄FN₃O₃

Molecular weight: 209.14

Ref: 4Z-A-111065

7-Fluoro-6-nitro-1H-quinazolin-4-one

CAS: 162012-69-3

7-Fluoro-6-nitro-1H-quinazolin-4-one

Purity: 98%

Color and Shape: Solid

Molecular weight: 209.13g/mol

Ref: 54-PC56920

7-fluoro-6-nitro-3,4-dihydroquinazolin-4-one

CAS: 162012-69-3

Purity: 98%

Molecular weight: 209.02

Ref: 10-F069168

7-Fluoro-6-nitro-4-hydroxyquinazoline

CAS: 162012-69-3

Formula: C₈H₄FN₃O₃

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 209.136

Ref: 10-F317809

7-Fluoro-6-nitroquinazolin-4(3H)-one

Controlled Product

CAS: 162012-69-3

Applications 7-Fluoro-6-nitroquinazolin-4(3H)-one, is an intermediate in the preparation of kinase inhibitors, such as ATP Site inhibitors of the Tyrosine Kinase activity of the epidermal growth factor receptor.
References Lee, K., et al.: Bioorg. Med. Chem., 17, 3152 (2009); Rewcastle, G., et al.: J. Med. Chem., 39, 918 (1996);

Formula: C₈H₄FN₃O₃

Color and Shape: Neat

Molecular weight: 209.13

Ref: TR-F594900

Afatinib Impurity 33

CAS: 162012-69-3

Formula: C₈H₄FN₃O₃

Molecular weight: 209.14

Ref: ST-EA-CP-A50043