CAS 1620401-83-3

UNC0379 TFA

CAS: 1620401-83-3

UNC0379 TFA is a selective chemical inhibitor, which is a synthetic small molecule specifically designed to target bromodomain and extra-terminal (BET) proteins. It is derived from a well-characterized pharmacological scaffold and is synthesized using established organic chemistry techniques. Its mode of action involves competitively binding to the acetyl-lysine recognition pocket of bromodomains, thereby preventing their interaction with acetylated histones. This inhibition disrupts the assembly of transcriptional machinery, hence modulating gene expression.

Formula: C₂₅H₃₆F₃N₅O₄

Purity: Min. 95%

Molecular weight: 527.58 g/mol

Ref: 3D-VPC40183

UNC0379 TFA

CAS: 1620401-83-3

UNC0379 TFA inhibits SETD8 (IC50: 7.3 μM), selective for 15+ methyltransferases.

Formula: C₂₅H₃₆F₃N₅O₄

Color and Shape: Solid

Molecular weight: 527.589

Ref: TM-T63705