mPEG12-Br, or methoxy poly(ethylene glycol) bromide, is a chemical compound characterized by its polyether structure, which consists of a polyethylene glycol (PEG) backbone with a terminal bromine atom. This compound typically features a molecular weight corresponding to a PEG chain of approximately 12 repeating units, contributing to its hydrophilicity and solubility in water and various organic solvents. The presence of the bromine atom makes it a reactive species, allowing for further chemical modifications and conjugation with other molecules, which is particularly useful in bioconjugation and drug delivery applications. mPEG12-Br is often utilized in the synthesis of polymeric materials, surfactants, and as a linker in biochemistry and materials science. Its properties, such as low toxicity and biocompatibility, make it suitable for biomedical applications, including the development of hydrogels and nanoparticles. Overall, mPEG12-Br serves as a versatile building block in various chemical and pharmaceutical research fields.

m-PEG12-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

mPEG12-Br

1620461-89-3: mPEG12-Br, or methoxy poly(ethylene glycol) bromide, is a chemical compound characterized by its polyether structure, which consists of a polyethylene glycol (PEG) backbone with a terminal bromine atom. This compound typically features a molecular weight corresponding to a PEG chain of approximately 12 repeating units, contributing to its hydrophilicity and solubility in water and various organic solvents. The presence of the bromine atom makes it a reactive species, allowing for further chemical modifications and conjugation with other molecules, which is particularly useful in bioconjugation and drug delivery applications. mPEG12-Br is often utilized in the synthesis of polymeric materials, surfactants, and as a linker in biochemistry and materials science. Its properties, such as low toxicity and biocompatibility, make it suitable for biomedical applications, including the development of hydrogels and nanoparticles. Overall, mPEG12-Br serves as a versatile building block in various chemical and pharmaceutical research fields.

37-Bromo-2,5,8,11,14,17,20,23,26,29,32,35-dodecaoxaheptatriacontane

<p>m-PEG12-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

CAS 1620461-89-3

mPEG12-Br

37-Bromo-2,5,8,11,14,17,20,23,26,29,32,35-dodecaoxaheptatriacontane

Ref: 54-OR1072681

m-PEG12-Br

Ref: TM-T18135

m-PEG12-Br

Ref: 10-F570425