CAS 162054-19-5

5-(4-Fluorophenyl)-1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

Description:

5-(4-Fluorophenyl)-1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazole, with CAS number 162054-19-5, is a synthetic organic compound characterized by its pyrazole core, which is a five-membered ring containing two nitrogen atoms. This compound features a trifluoromethyl group and a fluorophenyl substituent, contributing to its unique electronic properties and potential biological activity. The presence of a methylsulfonyl group enhances its solubility and may influence its reactivity and interaction with biological targets. Typically, compounds of this nature are studied for their potential applications in pharmaceuticals, particularly in the development of anti-inflammatory or analgesic agents. The molecular structure suggests that it may exhibit significant lipophilicity due to the presence of multiple aromatic rings and fluorinated groups, which can affect its pharmacokinetics. Additionally, the compound's stability and reactivity can be influenced by the electron-withdrawing nature of the trifluoromethyl and sulfonyl groups, making it a subject of interest in medicinal chemistry and material science.

Formula: C₁₇H₁₂F₄N₂O₂S

InChI: InChI=1S/C17H12F4N2O2S/c1-26(24,25)14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3

InChI key: InChIKey=JHBIMJKLBUMNAU-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=NN(C(=C1)C2=CC=C(F)C=C2)C3=CC=C(S(C)(=O)=O)C=C3

Synonyms:

• 1H-Pyrazole, 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-
• 5-(4-Fluorophenyl)-1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazole
• 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole
• Sc-58125

1H-Pyrazole, 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-

CAS: 162054-19-5

Formula: C₁₇H₁₂F₄N₂O₂S

Purity: %

Color and Shape: Solid

Molecular weight: 384.3480

Ref: IN-DA001SON

SC-58125

CAS: 162054-19-5

SC-58125

Purity: ≥98%

Molecular weight: 384.35g/mol

Ref: 54-BUP10456

SC-58125

CAS: 162054-19-5

Formula: C₁₇H₁₂N₂SO₂F₄

Molecular weight: 384.35

Ref: 7W-GK0606

SC-58125

CAS: 162054-19-5

SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. SC-58125 exhibits antitumor activity, and also inhibits oedema at sites of inflammation.

Formula: C₁₇H₁₂F₄N₂O₂S

Purity: 99.57%

Color and Shape: Solid

Molecular weight: 384.35

Ref: TM-T23333

SC-58125

Controlled Product

CAS: 162054-19-5

Applications SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor with anti-inflammatory properties. SC-58125 blocks edema and hyperalgesia without causing gastric mucosal damage. SC-58125 also displays antitumor activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References William, C.S. et al.: Neoplasmia, 3, 428 (2001); Gierse, J.K. et al.: J. Biol. Chem., 271, 15810 (1996); Brideau, C. et al.: Inflamm. Res., 45, 68 (1996);

Formula: C₁₇H₁₂F₄N₂O₂S

Color and Shape: Neat

Molecular weight: 384.35

Ref: TR-S199915