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CAS 162204-30-0

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5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine

Description:
5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is a modified nucleoside that features a fluorine atom at the 5' position of the ribose sugar, which can enhance its stability and bioactivity. The presence of the isopentyloxycarbonyl group at the N4 position of the cytidine base contributes to its lipophilicity, potentially improving cellular uptake and bioavailability. This compound is of interest in medicinal chemistry and pharmaceutical research, particularly in the development of antiviral and anticancer agents, as modifications to nucleosides can influence their interaction with nucleic acids and enzymes. The fluorine substitution may also affect the compound's binding affinity and selectivity for target enzymes or receptors. Overall, 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine exemplifies the strategic modifications made to nucleosides to enhance their therapeutic potential while maintaining structural integrity.
Formula:C15H22FN3O6
InChI:InChI=1/C15H22FN3O6/c1-7(2)4-5-24-15(23)18-12-9(16)6-19(14(22)17-12)13-11(21)10(20)8(3)25-13/h6-8,10-11,13,20-21H,4-5H2,1-3H3,(H,17,18,22,23)/t8-,10+,11?,13-/m1/s1
Synonyms:
  • [1-(5-Deoxy--D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-carbamic Acid 3-Methylbutyl Ester
  • 5'-Deoxy-5-fluoro-N-[(3-methylbutoxy)carbonyl]cytidine
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